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Product Info Summary
| SKU: | A02327-1 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-NSD1 Antibody
View all KMT3B/NSD1 Antibodies
SKU/Catalog Number
A02327-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-NSD1 Antibody catalog # A02327-1. Tested in WB applications. This antibody reacts with Human,Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-NSD1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02327-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from Internal of human HEXIM1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02327-1 is reactive to Nsd1 in Human, Mouse
Applications
A02327-1 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
284.084kDa
Background of KMT3B/NSD1
Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.
Kusuhara M., Biomed. Res. 20:273-279(1999).
Wittmann B.M., Cancer Res. 63:5151-5158(2003).
Ouchida R., Genes Cells 8:95-107(2003).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-NSD1 Antibody A02327-1
Western blot analysis of extracts of various cellsProtein Target Info & Infographic
Gene/Protein Information For Nsd1 (Source: Uniprot.org, NCBI)
Gene Name
Nsd1
Full Name
Histone-lysine N-methyltransferase, H3 lysine-36 specific
Weight
284.084kDa
Superfamily
class V-like SAM-binding methyltransferase superfamily
Alternative Names
Androgen receptor coactivator 267 kDa protein; Androgen receptor-associated protein of 267 kDa; ARA267STO; DKFZp666C163; EC 2.1.1.43; FLJ10684; FLJ22263; FLJ44628; H3 lysine-36 and H4 lysine-20 specific; KMT3BSotos syndrome; Lysine N-methyltransferase 3B; NR-binding SET domain-containing protein; nuclear receptor binding SET domain protein 1 Nsd1|AI528500, KMT3B|nuclear receptor-binding SET-domain protein 1|histone-lysine N-methyltransferase, H3 lysine-36 specific|H3-K36-HMTase|H4-K20-HMTase|NR-binding SET domain-containing protein|histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific|nuclear receptor-binding SET domain-containing protein 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Nsd1, check out the Nsd1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Nsd1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-NSD1 Antibody (A02327-1)
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No publications found for A02327-1
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