Anti-Periostin/POSTN Antibody

Product Name

Anti-Periostin/POSTN Antibody

View all Periostin/OSF-2 Antibodies

SKU/Catalog Number

PA2048

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Periostin/POSTN Antibody catalog # PA2048. Tested in WB applications. This antibody reacts with Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Periostin/POSTN Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2048)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of mouse Periostin, identical to the related rat sequence, and different from the related human sequence by three amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2048 is reactive to POSTN in Mouse, Rat

Applications

PA2048 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

93 kDa

Calculated molecular weight

93.314kDa

Background of Periostin/OSF-2

POSTN (Periostin), also known as PN or OSF2, is a protein that in humans is encoded by the POSTN gene. The International Radiation Hybrid Mapping Consortium mapped the POSTN gene to chromosome 13. Gillan et al. (2002) found that purified recombinant PN supported adhesion of ovarian epithelial cells. Shao et al. (2004) found that periostin was overexpressed by the majority of human primary breast cancers examined. Transfected tumor cell lines overexpressing periostin showed accelerated growth and angiogenesis as xenografts in immunocompromised animals. Kuhn et al. (2007) showed that extracellular periostin induced reentry of differentiated mammalian cardiomyocytes into the cell cycle.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Mouse, Rat

Validation Images & Assay Conditions

Click image to see more details

Anti-Periostin antibody, PA2048, Western blotting
All lanes: Anti Periostin (PA2048) at 0.5ug/ml
WB: Mouse Cardiac Muscle Tissue Lysate at 50ug
Predicted bind size: 93KD
Observed bind size: 93KD

Gene/Protein Information For POSTN (Source: Uniprot.org, NCBI)

Alternative Names

Fasciclin I-like; MGC119510; MGC119511; OSF2; OSF-2; OSF-2osteoblast specific factor 2 (fasciclin I-like); OSF2periodontal ligament-specific periostin; Osteoblast-specific factor 2; PDLPOSTN; periostin isoform thy2; periostin isoform thy4; periostin isoform thy6; periostin isoform thy8; Periostin; periostin, osteoblast specific factor; PNRP11-412K4.1; POSTN; TRIF52 POSTN OSF-2, OSF2, PDLPOSTN, PN periostin periostin|osteoblast specific factor 2 (fasciclin I-like)|periodontal ligament-specific periostin|periostin, osteoblast specific factor

For more info on POSTN, check out the POSTN Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for POSTN: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Take me to the POSTN Infographic

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