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- Table of Contents
TP53 antibody (RP1034) performs well in IHC and shows reactivity with Human, Mouse, Rat.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
- Over 5 Publications
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Anti-P Glycoprotein Picoband antibody, RP1034-5.JPG
IHC(P): Rat Kidney Tissue
IHC(P): Rat Kidney Tissue
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Anti-P Glycoprotein/ABCB1 Antibody
TP53 antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human, Mouse, Rat | Rabbit | IHC |
Tested Applications
TP53 antibody was positively detected by IHC in:
Human Lung Cancer Tissue, Mouse Kidney Tissue, Rat Kidney Tissue
Use TE buffer pH 9.0 for antigen retrieval; (*) citrate buffer pH 6.0 is an alternative.
TP53 antibody was positively detected by IHC-F in:
Mouse Intestine Tissue, Rat Kidney Tissue
Recommend Dilution
Application
Dilution
Species
Immunohistochemistry (Frozen Section)
0.5-1μg/ml
Mouse, Rat, -
Immunohistochemistry (Paraffin-embedded Section)
0.5-1μg/ml
Human, Mouse, Rat
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Reactive Data
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IHC
IF
Human
Tested
Recommend
Mouse
Tested
Recommend
Rat
Tested
Recommend
Monkey
Predicted
Predicted
Product Information
Product Name
Anti-P Glycoprotein/ABCB1 Antibody
View all TP53 Antibodies
View all TP53 Antibodies
Form
Lyophilized
Uniprot
Gene ID
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Host
Rabbit
Contents
Each vial contains antibody formulated with stabilizing components, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
*This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
*This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human P Glycoprotein, different from the related rat sequence by twelve amino acids.
Cross-Reactivity
No cross-reactivity with other proteins
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Calculated Molecular Weight
141.5 kDa
Background of TP53
P-GP, also called ABCB1 or PGY1, is a glycoprotein that in humans is encoded by the ABCB1 gene. It is mapped to 7q21.12. P-GP is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily. It is an important protein of the cell membrane that pumps many foreign substances out of cells. More formally, it is an ATP-dependent drug efflux pump with broad substrate specificity. P-GP is an ATP-dependent drug efflux pump forxenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood–brain barrier.
Cite This Product
Anti-P Glycoprotein/ABCB1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # RP1034)
Antibody Homology Across Species
The results generated by this homology analysis tool for commonly used animal species are shown below. For unlisted species, please refer to the homology analysis between the immunogen sequence and the corresponding species.
A homology of ≥90% is recommended. Generally, higher homology indicates a greater potential for cross-species reactivity. However, protein expression levels may vary among different species, tissues, and cell types. Therefore, the homology analysis results are for reference only and do not guarantee antibody cross-reactivity or experimental performance.
Human
100%
High Homology
Monkey
93%
High Homology
Dog
83%
Moderate Homology
Sheep
73%
Moderate Homology
Mouse
70%
Moderate Homology
Rat
70%
Moderate Homology
Cow
70%
Moderate Homology
Rabbit
67%
Low homology
Zebrafish
27%
Low homology
Drosophila
23%
Low homology
Homology ≥ 90%High Homology
70% ≤ Homology < 90%Moderate Homology
Homology < 70%Low homology
Protocols
Immunohistochemistry (IHC) protocol for TP53 antibody
Publications
Application:
Species:
Gut Microbiota Alter Colonic Expression of Genes Encoding Drug Transporters and Drug-Metabolizing Enzymes in Mice
Published: 2026-08-24
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Application: IF
Impact Factor: 5.60
Species: Mouse
PMID: 42737486
Combined effects of low‑dose gambogic acid and NaI131 in drug‑resistant non‑small cell lung cancer cells
Published: 2021-06-04
Journal: Oncology Letters
Application: WB
Impact Factor: 2.97
Species: Human
PMID: 34149899
Downregulation of cytokeratin 18 enhances BCRP-mediated multidrug resistance through induction of epithelial-mesenchymal transition and predicts poor prognosis in breast cancer
Published: 2019-03-15
Journal: ONCOLOGY REPORTS
Application: WB
Impact Factor: 3.04
Species: Human
PMID: 30896886
Overexpression of ILK promotes temozolomide resistance in glioma cells
Published: 2017-01-26
Journal: Molecular Medicine Reports
Application: WB
Impact Factor: 1.69
Species: Human
PMID: 28138714
Gambogic Acid as a Non-Competitive Inhibitor of ATP-Binding Cassette Transporter B1 Reverses the Multidrug Resistance of Human Epithelial Cancers by Promoting ATP-Binding Cassette Transporter B1 Protein Degradation
Published: 2012-07-03
Journal: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Application: WB
Impact Factor: 2.18
Species: Human
PMID: 22759348
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Product Promise
We promise Anti-P Glycoprotein/ABCB1 Antibody performs excellently in relevant applications for IHC. If it doesn't perform as promised, we will refund the product. Learn more
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RP1034
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00
Troubleshooting
Boster Guarantee
Guaranteed product quality
We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 11, 2026