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Product Info Summary
| SKU: | M04136 |
|---|---|
| Size: | 100 μl |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IP, IF, ICC, WB |
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Product info
Product Name
Anti-p23 Monoclonal Antibody
View all p23/PTGES3 Antibodies
SKU/Catalog Number
M04136
Size
100 μl
Form
Liquid
Description
Boster Bio Anti-p23 Monoclonal Antibody catalog # M04136. Tested in WB, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-p23 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M04136)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Clonality
Monoclonal
Clone Number
ACAH-16
Isotype
Rabbit IgG
Immunogen
A synthesized peptide derived from human p23 Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M04136 is reactive to PTGES3 in Human, Mouse, Rat
Applications
M04136 is guaranteed for IP, IF, ICC, WB Boster Guarantee
Observed Molecular Weight
47 kDa
Calculated molecular weight
18.697kDa
Background of p23/PTGES3
Plays a major role in tight junction-specific obliteration of the intercellular space.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:1000-1:5000
ICC/IF 1:50-1:200
IP 1:50
Validation Images & Assay Conditions
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Western blot analysis of p23 expression in (1) HeLa cell lysate; (2) NIH/3T3 cell lysate; (3) PC12 cell lysate.
Protein Target Info & Infographic
Gene/Protein Information For PTGES3 (Source: Uniprot.org, NCBI)
Gene Name
PTGES3
Full Name
Prostaglandin E synthase 3
Weight
18.697kDa
Superfamily
p23/wos2 family
Alternative Names
CPGES; cPGESp23; Cytosolic prostaglandin E2 synthase; Hsp90 co-chaperone; p23; P23cytosolic prostaglandin E synthase; Progesterone receptor complex p23; prostaglandin E synthase 3 (cytosolic); prostaglandin E synthase 3; PTGES3; TEBP; TEBPEC 5.3.99.3; Telomerase-binding protein p23; unactive progesterone receptor, 23 kD PTGES3 P23, TEBP, cPGES prostaglandin E synthase 3 prostaglandin E synthase 3|Hsp90 co-chaperone|cytosolic prostaglandin E synthase|cytosolic prostaglandin E2 synthase|progesterone receptor complex p23|prostaglandin E synthase 3 (cytosolic)|telomerase-binding protein p23|unactive progesterone receptor, 23 kD
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PTGES3, check out the PTGES3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PTGES3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-p23 Monoclonal Antibody (M04136)
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No publications found for M04136
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Customer Reviews
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Customer Q&As
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3 Customer Q&As for Anti-p23 Monoclonal Antibody
Question
Can you help my question with product M04136, anti-p23 Monoclonal antibody. I was wondering if it would be possible to conjugate this antibody with biotin. I would need it to be without BSA or sodium azide. I am planning on using a buffer exchange of sodium azide with PBS only. Would there be problems for me to conjugate the antibody and store it in -20 degrees in small aliquots?
Verified Customer
Verified customer
Asked: 2019-11-13
Answer
We do not advise storing this antibody with PBS buffer only in -20 degrees. If you want to store it in -20 degrees it is best to add some cryoprotectant like glycerol. If you want carrier free M04136 anti-p23 Monoclonal antibody, we can provide it to you in a special formula with trehalose and/or glycerol. These molecules will not interfere with conjugation chemistry and provide a good level of protection for the antibody from degradation. Please be sure to specify this in your purchase order.
Boster Scientific Support
Answered: 2019-11-13
Question
Is this M04136 anti-p23 Monoclonal antibody reactive to the isotypes of PTGES3?
K. Dhar
Verified customer
Asked: 2017-08-31
Answer
The immunogen of M04136 anti-p23 Monoclonal antibody is A synthesized peptide derived from human p23 Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?
Boster Scientific Support
Answered: 2017-08-31
Question
Would anti-p23 Monoclonal antibody M04136 work for IF with cervix carcinoma?
T. Collins
Verified customer
Asked: 2013-03-01
Answer
According to the expression profile of cervix carcinoma, PTGES3 is highly expressed in cervix carcinoma. So, it is likely that anti-p23 Monoclonal antibody M04136 will work for IF with cervix carcinoma.
Boster Scientific Support
Answered: 2013-03-01
