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Product Info Summary
| SKU: | M01244-1 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-p57 CDKN1C Monoclonal Antibody
SKU/Catalog Number
M01244-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-p57 CDKN1C Monoclonal Antibody catalog # M01244-1. Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-p57 CDKN1C Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01244-1)
Host
Mouse
Contents
Ascitic fluid containing 0.03% sodium azide.
Clonality
Monoclonal
Clone Number
3E3
Isotype
IgG
Immunogen
Purified recombinant fragment of human p57 expressed in E. Coli.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
M01244-1 is reactive to CDKN1C in Human
Applications
M01244-1 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
32.177kDa
Background of p57 Kip2
TRPC6, also known as TRP6, short transient receptor potential channel 6 and transient receptor potential cation channel subfamily C member 6, is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC6 is probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. It is activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C and may not to be activated by intracellular calcium store depletion. Defects in this gene are a cause of focal segmental glomerulosclerosis (FSGS). Expression of this protein has been reported in tissues such as placenta, lung, spleen, ovary, small intestine, and renal podocytes. Immunohistochemistry studies using polyclonal antibodies to this target have shown moderate to strong staining in cell types such as neurons, breast, respiratory, squamous and prostate epithelium, epidermis, placental trophoblasts, dendritic cells, and subsets of immune cells, and faint to moderate staining of adrenal, colon, ganglion cells, hepatocytes, heart, and testis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
ELISA 1:10000
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-p57 CDKN1C Monoclonal Antibody M01244-1
Western Blot (WB) analysis using p57 Monoclonal Antibody against HEK293 (1) and CDKN1C-hIgGFc transfected HEK293 (2) cell lysate.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For CDKN1C (Source: Uniprot.org, NCBI)
Gene Name
CDKN1C
Full Name
Cyclin-dependent kinase inhibitor 1C
Weight
32.177kDa
Superfamily
CDI family
Alternative Names
Beckwith-Wiedemann syndrome; BWS; cyclin-dependent kinase inhibitor 1C (p57, Kip2); cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; KIP2BWCR; p57; p57Kip2; WBS CDKN1C BWCR, BWS, KIP2, WBS, p57, p57Kip2 cyclin dependent kinase inhibitor 1C cyclin-dependent kinase inhibitor 1C|cyclin-dependent kinase inhibitor 1C (p57, Kip2)|cyclin-dependent kinase inhibitor p57
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CDKN1C, check out the CDKN1C Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CDKN1C: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-p57 CDKN1C Monoclonal Antibody (M01244-1)
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No publications found for M01244-1
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Customer Reviews
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