Anti-Peroxiredoxin 1 PRDX1 Monoclonal Antibody

Product Name

Anti-Peroxiredoxin 1 PRDX1 Monoclonal Antibody

View all Peroxiredoxin 1 Antibodies

SKU/Catalog Number

M01845-2

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Peroxiredoxin 1 PRDX1 Monoclonal Antibody catalog # M01845-2. Tested in IF, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Peroxiredoxin 1 PRDX1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01845-2)

Host

Mouse

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Monoclonal

Clone Number

80000000

Isotype

IgG

Immunogen

Recombinant Protein

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M01845-2 is reactive to PRDX1 in Human, Mouse, Rat

Applications

M01845-2 is guaranteed for IF, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

22.11kDa

Background of Peroxiredoxin 1

Indoleamine 2, 3-dioxygenase1 (IDO1) is a 41-42 kD intracellular enzyme that catabolizes tryptophan into kynurenine. IDO1 modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. IDO1 effects on immune suppression are due to decreased tryptophan availability and the generation of tryptophan metabolites, resulting in negative effects on T lymphocytes, including proliferation, function and survival. IDO1 may be involved in the suppression of the immune response to tumors, and blocking the IDO1 pathway may be a potential target for immuno and cancer therapy. IDO1 is expressed in a wide variety of tissues and can be upregulated by interferon gamma and other inflammatory cytokines.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:1000-3000
IF 1:100-200

Validation Images & Assay Conditions

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Figure 2. Immunohistochemistry validation of PRDX1 using Anti-Peroxiredoxin 1 PRDX1 Monoclonal Antibody (M01845-2).

Immunohistochemical analysis of human-lung tissue. Anti-Peroxiredoxin 1 at 1:200 (4°C

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Figure 3. Immunohistochemistry validation of PRDX1 using Anti-Peroxiredoxin 1 PRDX1 Monoclonal Antibody (M01845-2).

Immunohistochemical analysis of human uterus cancer tissue. Anti-Peroxiredoxin 1 at 1:200 (4°C

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Figure 1. Western blotting validation for Anti-Peroxiredoxin 1 PRDX1 Monoclonal Antibody M01845-2

Western blot (WB) analysis of Peroxiredoxin 1 monoclonal antibody.
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration

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Figure 4. Immunofluorescent staining data of PRDX1 using Anti-Peroxiredoxin 1 PRDX1 Monoclonal Antibody (M01845-2).

Immunofluorescence (IF) analysis of HeLa with antibody (Left) and DAPI (Right) diluted at 1:100.

Gene/Protein Information For PRDX1 (Source: Uniprot.org, NCBI)

Alternative Names

EC 1.11.1; EC 1.11.1.15; Natural killer cell-enhancing factor A; natural killer-enhancing factor A; NKEFA; NKEF-A; PAG; PAGAMSP23; PAGB; Peroxiredoxin 1; peroxiredoxin-1; PRDX1; proliferation-associated gene A; Proliferation-associated gene protein; PRX1; PRXI; TDPX2; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2 PRDX1 MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2 peroxiredoxin 1 peroxiredoxin-1|epididymis secretory sperm binding protein|natural killer cell-enhancing factor A|natural killer-enhancing factor A|proliferation-associated gene A|proliferation-associated gene protein|thioredoxin peroxidase 2|thioredoxin-dependent peroxide reductase 2|thioredoxin-dependent peroxiredoxin 1

For more info on PRDX1, check out the PRDX1 Infographic

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In this infographic, you will see the following information for PRDX1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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