Anti-PTPRK Antibody

Product Name

Anti-PTPRK Antibody

View all PTPRK Antibodies

SKU/Catalog Number

A05486

Size

100ul

Form

Liquid

Description

Boster Bio Anti-PTPRK Antibody catalog # A05486. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-PTPRK Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05486)

Host

Rabbit

Contents

Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human PTPRK protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A05486 is reactive to PTPRK in Human, Mouse

Applications

A05486 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

111 kDa

Calculated molecular weight

162.102kDa

Background of PTPRK

Isoform GANP:Essential for the generation of high-affinity B-cells against T-cell-dependent antigens by affecting somatic hypermutation at the IgV-regions. May have stimulation-dependent DNA primase activity that would generate extra RNA primers in very rapidely proliferating cells and would support clonal expansion of differentiating B-cells By similarity. Involved in the nuclear export of poly(A)-containing mRNAs by acting as a scaffold for the TREX-2 complex. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. Isoform MCM3AP:Acetyltransferase targeting MCM3. Inhibits initiation of DNA replication, but not elongation.

Nobuo Sakaguchi, J. Immunol., Apr 2005; 174: 4485 - 4494.
Kazuhiko Kuwahara, Blood, Apr 2000; 95: 2321 - 2328.
Y Kono, K Maeda, Genes Cells, Aug 2002; 7: 821 - 834.
Kazuhiko Kuwahara, PNAS, Aug 2001; 98: 10279.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-2000 ELISA 1:5000-20000

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For PTPRK (Source: Uniprot.org, NCBI)

Alternative Names

DKFZp686C2268; DKFZp779N1045; EC 3.1.3.48; protein tyrosine phosphatase kappa, protein tyrosine phosphatase kappa; protein tyrosine phosphatase, receptor type, K; Protein-tyrosine phosphatase kappa; protein-tyrosine phosphatase, receptor type, kappa; PTPK; receptor type, K (R-PTP-KAPPA; receptor-type tyrosine-protein phosphatase kappa PTPRK R-PTP-kappa protein tyrosine phosphatase receptor type K receptor-type tyrosine-protein phosphatase kappa|dJ480J14.2.1 (protein tyrosine phosphatase, receptor type, K (R-PTP-KAPPA, protein tyrosine phosphatase kappa , protein tyrosine phosphatase kappa|protein-tyrosine phosphatase kappa|protein-tyrosine phosphatase, receptor type, kappa

For more info on PTPRK, check out the PTPRK Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PTPRK: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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