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Product Info Summary
| SKU: | A09261-1 |
|---|---|
| Size: | 80 µl |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | IF, IHC-P, WB |
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Product info
Product Name
Anti-SOCS4 Antibody (Center)
SKU/Catalog Number
A09261-1
Size
80 µl
Description
Boster Bio Anti-SOCS4 Antibody (Center) (Catalog # A09261-1). Tested in WB, IF, IHC-P application(s). This antibody reacts with Human.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-SOCS4 Antibody (Center) (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09261-1)
Host
Rabbit
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
This SOCS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 amino acids from the Central region of human SOCS4.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A09261-1 is reactive to Socs4 in Human
Applications
A09261-1 is guaranteed for IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
49.918kDa
Background of SOCS-4
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IF: 1:10-1:50
WB: 1:1000
IHC-P: 1:10-1:50
Validation Images & Assay Conditions
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Confocal immunofluorescent analysis of SOCS4 Antibody (Center) with A2058 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).
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Western blot analysis of lysate from MCF-7 cell line,using SOCS4 Antibody (Center).A09261-1 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug per lane.
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SOCS4 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SOCS4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Protein Target Info & Infographic
Gene/Protein Information For Socs4 (Source: Uniprot.org, NCBI)
Gene Name
Socs4
Full Name
Suppressor of cytokine signaling 4
Weight
49.918kDa
Alternative Names
CIS4; DKFZp686J1568; SOCS4; SOCS-4; SOCS7; SOCS-7; SSI4; STAT4; suppressor of cytokine signaling 4; Suppressor of cytokine signaling 7SH2 domain containing SOCS box protein Socs4|3110032M18Rik, A730004F22Rik, AI427843, AU015727, AU015859, So, Socs7|suppressor of cytokine signaling 4|suppressor of cytokine signaling 4|SOCS-4|SOCS-7|suppressor of cytokine signaling 7|suppressor of cytokine signalling 4
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Socs4, check out the Socs4 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Socs4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SOCS4 Antibody (Center) (A09261-1)
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No publications found for A09261-1
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