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- Table of Contents
AKR1B1 Antibodies
AND AKR1B1 ELISA kits, AKR1B1 Proteins
Many biological assays use antibodies to detect AKR1B1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AKR1B1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AKR1B1 antibodies...
Designing a Western blot for AKR1B1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the AKR1B1 Western Blot GuideDesigning an IHC experiment for AKR1B1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the AKR1B1 IHC GuideAKR1B1 Infographic by Boster Bio
All AKR1B1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # PB10035
100 μg/vial
Cat # PB10035
100 μg/vial
Enzyme Activity, SDS-PAGE
$250
Cat # PROTP45376
Starting from 20ug
Cat # PROTP45376
Starting from 20ug
Enzyme Activity, SDS-PAGE
$234
Cat # PROTP15121
Starting from 20ug
Cat # PROTP15121
Starting from 20ug
AKR1B1 Overview
Facts about Aldo-keto reductase family 1 member B1.
Aldo-keto reductase family 1 member B1 (AKR1B1)
Catalyzes the NADPH-dependent reduction of a wide array of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. .
Gene Information
| Human | |
|---|---|
| Gene Name: | AKR1B1 |
| Uniprot: | P15121 |
| Entrez: | 231 |
Family
| Belongs to: |
|---|
| aldo/keto reductase family |
Alternative Names
ADR; Aldehyde reductase; Aldo-keto reductase family 1 member B1; aldo-keto reductase family 1, member B1 (aldose reductase); ALDR1aldose reductase; ALR2; ARaldehyde reductase 1; EC 1.1.1; EC 1.1.1.21; Lii5-2 CTCL tumor antigen; low Km aldose reductase; MGC1804
Molecular Weight
Mass (kDA):
35.853 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q33 |
| Sequence: | 7; NC_000007.14 (134442350..134459239, complement) |
Tissue Specificity
Highly expressed in embryonic epithelial cells (EUE) in response to osmotic stress.
Subcellular Localizations
Cytoplasm.
Diseases
- Diabetes Mellitus
- Malignant Neoplasms
- Complications Of Diabetes Mellitus
- Neoplasms
- Retinal Diseases
- Diabetes Mellitus, Non-insulin-dependent
- Diabetic Retinopathy
- Kidney Diseases
- Cataract
- Carcinoma
- Endometrial Polyp
- Diabetic Nephropathy
Pathways
- Pathogenesis
- Embryo Development
- Cell Proliferation
- Parturition
- Transport
- Blastocyst Formation
- Insemination
- Localization
- Methylation
- Secretion
- Fertilization
- Inflammatory Response
- Menstruation
PTMs
- Reduction
- Oxidation
- Phosphorylation
- Cleavage
Research Areas
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AKR1B1
bosterbio.com/bosterbio-gene-info-cards/AKR1B1
References
PMID: 2498333 by Bohren K.M., et al. The aldo-keto reductase superfamily. cDNAs and deduced amino acid sequences of human aldehyde and aldose reductases.
PMID: 2504709 by Chung S., et al. Cloning and sequence determination of human placental aldose reductase gene.
1 Publications of Boster AKR1B1 Antibodies & ELISA Kits
- PubMed ID: 10.18632/aging.103393, Loss of AKR1B10 promotes colorectal cancer cells proliferation and migration via...
*More publications can be found for each product on its corresponding product page