- Table of Contents
Over 100 substrate candidates have been reported so far, but for many of them, no isoform specificity was reported. AKT3 is the least researched AKT isoform.
|protein kinase superfamily|
|Sequence:||1; NC_000001.11 (243488233..243851079, complement)|
In adult tissues, it is highly expressed in brain, lung and kidney, but weakly in heart, testis and liver. In fetal tissues, it is highly expressed in heart, liver and brain and not at all in kidney.
Nucleus. Cytoplasm. Membrane; Peripheral membrane protein. Membrane-associated after cell stimulation leading to its translocation.