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- Table of Contents
BMP2 Antibodies
AND BMP2 ELISA kits, BMP2 Proteins
Many biological assays use antibodies to detect BMP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BMP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BMP2 antibodies...
Designing a Western blot for BMP2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the BMP2 Western Blot GuideBMP2 Infographic by Boster Bio
All BMP2 Products
Product
Figures
Specificity
Applications
Price
Anti-BMP2 Antibody Picoband®
25 Citations
Human, Rat
IHC, WB, ELISA (Cap)
$370
Cat # PB9687
100 μg/vial
Cat # PB9687
100 μg/vial
Human
ELISA
$499
Cat # FEK0311
96 wells/kit, with removable strips.
Cat # FEK0311
96 wells/kit, with removable strips.
Mouse
ELISA
$500
Cat # EZ0313
For 5 plates, 96 wells each, reagents only, plates are not included
Cat # EZ0313
For 5 plates, 96 wells each, reagents only, plates are not included
Mouse
ELISA
$499
Cat # FEK0313
96 wells/kit, with removable strips.
Cat # FEK0313
96 wells/kit, with removable strips.
Monkey
ELISA
$500
Cat # EZ0311-PR
5 plates/kit
Cat # EZ0311-PR
5 plates/kit
Horse
ELISA
$500
Cat # EZ0311-EQ
5 plates/kit
Cat # EZ0311-EQ
5 plates/kit
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00338-1
20μL, 40μL, 100μL, 200μL
Cat # M00338-1
20μL, 40μL, 100μL, 200μL
Rabbit BMP-2 ELISA Kit PicoKine®
1 Citations
Rabbit
ELISA
$399
Cat # EK0311-RB
96 wells/kit, with removable strips.
Cat # EK0311-RB
96 wells/kit, with removable strips.
Monkey
ELISA
$399
Cat # EK0311-PR
96 wells/kit, with removable strips.
Cat # EK0311-PR
96 wells/kit, with removable strips.
Pig
ELISA
$399
Cat # EK0311-PO
96 wells/kit, with removable strips.
Cat # EK0311-PO
96 wells/kit, with removable strips.
Equine
ELISA
$399
Cat # EK0311-EQ
96 wells/kit, with removable strips.
Cat # EK0311-EQ
96 wells/kit, with removable strips.
Bovine
ELISA
$399
Cat # EK0311-BV
96 wells/kit, with removable strips.
Cat # EK0311-BV
96 wells/kit, with removable strips.
Human
Cell Culture
$77
Cat # PROTP12643-7
5ug,20ug,100ug
Cat # PROTP12643-7
5ug,20ug,100ug
Canine
ELISA
$499
Cat # EK0313-CN
96 wells/kit, with removable strips.
Cat # EK0313-CN
96 wells/kit, with removable strips.
BMP2 Overview
Facts about Bone morphogenetic protein 2.
Bone morphogenetic protein 2 (BMP2)
Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway.
BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451).
Gene Information
| Human | |
|---|---|
| Gene Name: | BMP2 |
| Uniprot: | P12643 |
| Entrez: | 650 |
Family
| Belongs to: |
|---|
| TGF-beta family |
Alternative Names
BDA2; BMP2; BMP-2; BMP-2A; BMP2ABone morphogenetic protein 2A; bone morphogenetic protein 2; SSFSC
Molecular Weight
Mass (kDA):
44.702 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 20p12.3 |
| Sequence: | 20; NC_000020.11 (6767686..6780246) |
Tissue Specificity
Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.
Subcellular Localizations
Secreted.
Diseases
- Fracture
- Neoplasms
- Malignant Neoplasms
- Crest Syndrome
- Osteoporosis
- Hypertrophy
- Tissue Adhesions
- Heterotopic Ossification
- Calcinosis
- Skin Callus
- Inflammation
- Tumor Angiogenesis
- Nervousness
Interacting Proteins
- Acvr2a
- BMPR1A
- BMPR1B
- FSTL1
- HJV
- NOG
- RGMB
- TNFAIP6
Pathways
- Regeneration
- Osteoblast Differentiation
- Cell Proliferation
- Cell Differentiation
- Ossification
- Secretion
- Bone Resorption
- Localization
- Cell Growth
- Angiogenesis
- Pathogenesis
- Endochondral Ossification
- Bone Development
PTMs
- Phosphorylation
- Cleavage
- Acetylation
- Methylation
- Ubiquitination
- Glycosylation
- Demethylation
- Biotinylation
- Reduction
- Gamma-carboxylation
Research Areas
- Stem Cell Signaling Pathway
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BMP2
bosterbio.com/bosterbio-gene-info-cards/BMP2
References
PMID: 3201241 by Wozney J.M., et al. Novel regulators of bone formation: molecular clones and activities.
PMID: 9265423 by Yeung B., et al. Direct isoform analysis of high-mannose-containing glycoproteins by on-line capillary electrophoresis electrospray mass spectrometry.
82 Publications of Boster BMP2 Antibodies & ELISA Kits
- PubMed ID: PMID:26396672, Effects of sequentially released BMP-2 and BMP-7 from PELA microcapsule-based sc...
- PubMed ID: PMID:19098993, Bone morphogenetic protein-2: a potential regulator in scleral remodeling
- PubMed ID: 10.4238/2014.October.27.1, BMP-2 promotes chondrogenesis of rat adipose-derived stem cells by using a lenti...
- PubMed ID: 10.3892/mmr.2015.3705, MicroRNA-218, microRNA-191*, microRNA-3070a and microRNA-33 are responsive to me...
- PubMed ID: 10.3892/ijmm.2016.2636, Mechanical strain promotes osteoblastic differentiation through integrin-β1-med...
- PubMed ID: 10.3892/etm.2018.5950, Sevoflurane-induced memory impairment in the postnatal developing mouse brain
- PubMed ID: 10.3892/etm.2015.2391, Expression of β-site APP-cleaving enzyme 1 in the hippocampal tissue of an insu...
- PubMed ID: 10.3760/cma.j.issn.0366-6999.2009.04.0021, Construction and expression of a bicistronic vector containing human bone morpho...
- PubMed ID: 10.3233/THC-209006, Preliminary study on the electromagnetic field treatment of osteoporosis in rats
- PubMed ID: 10.2485/jhtb.28.303, Antibacterial and Biological Properties of a Micro-structured BMP-2/Chitosan/Hyd...
- PubMed ID: 10.2147/IJN.S167035, Thermally induced self-agglomeration 3D scaffolds with BMP-2-loaded core–shell...
- PubMed ID: 10.1126/sciadv.abf6654, Regulation of macrophage polarization through surface topography design to facil...
- PubMed ID: 10.1111/j.1440-1797.2012.01601.x, Involvement of parathyroid hormone‐related protein in vascular calcification o...
- PubMed ID: 10.1111/cpr.12796, The synergetic effect of bioactive molecule–loaded electrospun core‐shell fi...
- PubMed ID: 10.1097/BOT.0000000000001160, Effects of Episodic Alcohol Exposure on BMP2 Signaling During Tibia Fracture Hea...
- PubMed ID: 10.1089/ten.tea.2018.0342, A Biomimicking Polymeric Cryogel Scaffold for Repair of Critical-Sized Cranial D...
- PubMed ID: 10.1080/00365520902998661, Acid and bile salt up-regulate BMP4 expression in human esophageal epithelium ce...
- PubMed ID: 10.1039/C9NR07017F, Bone formation promoted by bone morphogenetic protein-2 plasmid-loaded porous si...
- PubMed ID: 10.1039/C9BM01352K, ONO-1301 loaded nanocomposite scaffolds modulate cAMP mediated signaling and ind...
- PubMed ID: 10.1038/srep28537, Effects of local delivery of BMP2, zoledronate and their combination on bone mic...
- PubMed ID: 10.1021/acsbiomaterials.9b01954, Mesoporous Hydroxyapatite Nanoparticles Mediate the Release and Bioactivity of B...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page