- Table of Content
Modulates B-cell activation answers. In association with SIGLEC10 might be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90.
Expressed in the central nervous system, in postmitotic cells of spinal cord, hindbrain, midbrain and forebrain. Expressed in epithelium during the development of non- neural tissues. Expressed in tooth development, specifically in mesenchymal cells differentiating into odontoblast in dental papilla, as well as in the developing eye and hair follicle.
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