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- Table of Contents
CELF1 Antibodies
AND CELF1 ELISA kits, CELF1 Proteins
Many biological assays use antibodies to detect CELF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CELF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CELF1 antibodies...
Designing a Western blot for CELF1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CELF1 Western Blot GuideDesigning an IHC experiment for CELF1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the CELF1 IHC GuideCELF1 Infographic by Boster Bio
All CELF1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M02163-1
100 μl/vial
Cat # M02163-1
100 μl/vial
CELF1 Overview
Facts about CUGBP Elav-like family member 1.
CUGBP Elav-like family member 1 (CELF1)
RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability.
Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition.
Gene Information
| Human | |
|---|---|
| Gene Name: | CELF1 |
| Uniprot: | Q92879 |
| Entrez: | 10658 |
Family
| Belongs to: |
|---|
| CELF/BRUNOL family |
Alternative Names
BRUNOL2; BRUNOL250 kDa nuclear polyadenylated RNA-binding protein; bruno-like 2; Bruno-like protein 2; CELF1; CUG RNA-binding protein; CUG triplet repeat, RNA binding protein 1; CUG triplet repeat, RNA-binding protein 1; CUG-BP- and ETR-3-like factor 1; CUGBP Elav-like family member 1; CUG-BP; CUGBP, Elav-like family member 1; CUGBP1; CUG-BP1; CUGBP1CUG triplet repeat RNA-binding protein 1; CUGBPCELF-1; D2Wsu101e; Deadenylation factor CUG-BP; EDEN-BP homolog; EDEN-BP; embryo deadenylation element binding protein; Embryo deadenylation element-binding protein homolog; HNAB50; NAB50; NAB50CUG-BP1
Molecular Weight
Mass (kDA):
52.063 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11p11.2 |
| Sequence: | 11; NC_000011.10 (47465937..47565539, complement) |
Tissue Specificity
Ubiquitous.
Subcellular Localizations
Nucleus. Cytoplasm. RNA-binding activity is detected in both nuclear and cytoplasmic compartments.
Diseases
- Myotonic Dystrophy
- Dystrophy
- Trinucleotide Repeat Expansion
- Neuromuscular Diseases
- Dystrophia Myotonica 1
- Malignant Neoplasms
- Muscular Dystrophy
- Dystrophia Myotonica 2
- Myopathy
- Neoplasms
- Neurodegenerative Disorders
- Myotonic Disorders
Pathways
- Translation
- Pathogenesis
- Rna Processing
- Fertilization
- Localization
- Cell Cycle
- Mrna Processing
- Cell Growth
- Hyperphosphorylation
- Aging
- Spermatogenesis
- Rna Splicing
- Regeneration
PTMs
- Phosphorylation
Research Areas
- Cancer
- Chromatin Research
- DNA replication, Transcription, Translation and Splicing
- Neurodegeneration
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CELF1
bosterbio.com/bosterbio-gene-info-cards/CELF1
References
PMID: 8948631 by Timchenko L.T., et al. Identification of a (CUG)n triplet repeat RNA-binding protein and its expression in myotonic dystrophy.
PMID: 10893231 by Good P.J., et al. A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator.