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- Table of Contents
Complement factor D Antibodies
AND CFD ELISA kits, Complement factor D Proteins
Many biological assays use antibodies to detect Complement factor D, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Complement factor D in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Complement factor D antibodies...
Designing a Western blot for Complement factor D? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CFD Western Blot GuideCFD Infographic by Boster Bio
All CFD Products
Product
Figures
Specificity
Applications
Price
Mouse
ELISA
$499
Cat # EK1420
96 wells/kit, with removable strips.
Cat # EK1420
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # EK1199
96 wells/kit, with removable strips.
Cat # EK1199
96 wells/kit, with removable strips.
Human, Mouse, Rat
ELISA, IHC, WB
$370
Cat # A01134-1
100 μg/vial
Cat # A01134-1
100 μg/vial
Human, Rabbit
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01134-1
100 μg
Cat # M01134-1
100 μg
CFD Overview
Facts about Complement factor D.
Complement factor D (CFD)
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternative pathway. Its function is homologous to that of C1s in the classical pathway.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | CFD |
| Uniprot: | P00746 |
| Entrez: | 1675 |
Family
| Belongs to: |
|---|
| peptidase S1 family |
Alternative Names
Adipsin; ADN; ADNcomplement factor D; AMBP-1; C3 convertase activator; CFD; complement factor D (adipsin); complement factor D preproprotein; Complement Factor D; D component of complement (adipsin); DF; EC 3.4.21; EC 3.4.21.46; PFD; Properdin factor DADIPSIN
Molecular Weight
Mass (kDA):
27.033 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.3 |
| Sequence: | 19; NC_000019.10 (859664..863641) |
Subcellular Localizations
Secreted.
Diseases
- Aneurysm
- Stenosis
- Hemolysis (disorder)
- Intracranial Aneurysm
- Thrombosis
- Atherosclerosis
- Cerebral Aneurysm
- Thrombus
- Inhalation Exposure
- Hyperplasia
- Malignant Neoplasms
- Dental Plaque
Pathways
- Transport
- Segmentation
- Pathogenesis
- Swimming
- Cell Growth
- Fermentation
- Flight
- Platelet Activation
- Localization
- Cell Proliferation
- Coagulation
- Flocculation
- Locomotion
PTMs
- Oxidation
- Nitration
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CFD
bosterbio.com/bosterbio-gene-info-cards/CFD
References
PMID: 1374388 by White R.T., et al. Human adipsin is identical to complement factor D and is expressed at high levels in adipose tissue.
PMID: 6383466 by Niemann M.A., et al. Amino acid sequence of human D of the alternative complement pathway.
1 Publications of Boster Complement factor D Antibodies & ELISA Kits
- PubMed ID: 32018039, Chen G,Wang Q,Li Z,Yang Q,Liu Y,Du Z,Zhang G,Song Y.Circular RNA CDR1as promotes...
*More publications can be found for each product on its corresponding product page