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- Table of Contents
DDX6 Antibodies
AND DDX6 ELISA kits, DDX6 Proteins
Many biological assays use antibodies to detect DDX6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DDX6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DDX6 antibodies...
Designing a Western blot for DDX6? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the DDX6 Western Blot GuideDesigning an IHC experiment for DDX6? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the DDX6 IHC GuideDDX6 Infographic by Boster Bio
All DDX6 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # A03826-1
100 μg/vial
Cat # A03826-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # M03826-1
100 μg/vial
Cat # M03826-1
100 μg/vial
DDX6 Overview
Facts about Probable ATP-dependent RNA helicase DDX6.
Probable ATP-dependent RNA helicase DDX6 (DDX6)
In the process of mRNA degradation, plays a role in mRNA decapping (PubMed:16364915). Blocks autophagy in nutrient-rich states by repressing the expression of ATG-related genes through degration of their transcripts (PubMed:26098573).
.
Gene Information
| Human | |
|---|---|
| Gene Name: | DDX6 |
| Uniprot: | P26196 |
| Entrez: | 1656 |
Family
| Belongs to: |
|---|
| DEAD box helicase family |
Alternative Names
ATP-dependent RNA helicase p54; DEAD (Asp-Glu-Ala-Asp) box polypeptide 6; DEAD box protein 6; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6 (RNA helicase, 54kD); EC 3.6.1; EC 3.6.4.13; FLJ36338; HLR2DEAD box-6; Oncogene RCK; probable ATP-dependent RNA helicase DDX6; RCKP54
Molecular Weight
Mass (kDA):
54.417 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q23.3 |
| Sequence: | 11; NC_000011.10 (118747763..118791696, complement) |
Tissue Specificity
Abundantly expressed in most tissues.
Subcellular Localizations
Cytoplasm, P-body. Cytoplasm. Nucleus. Upon cellular stress, relocalizes to stress granules (PubMed:26184334).
Diseases
- Neoplasms
- Lymphoma
- Chromosomal Translocation
- Malignant Neoplasms
- B-cell Lymphomas
- Malignant Paraganglionic Neoplasm
- Carcinogenesis
- Hepatitis
- Hepatitis C
- Cell Transformation, Neoplastic
- Neuroblastoma
- Myeloid Leukemia
Interacting Proteins
- AES
- AGO2
- ATXN2
- BIRC7
- CALCOCO2
- CEP70
- DCP1A
- EDC3
- EIF4ENIF1
- GOLGA2
Pathways
- Translation
- Localization
- Mrna Processing
- Cell Proliferation
- Rna Interference
- Gene Silencing
- S Phase
- Cell Growth
- Pathogenesis
- Ribosome Assembly
- Sexual Reproduction
- Nuclear Export
- Cell Cycle Arrest
PTMs
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DDX6
bosterbio.com/bosterbio-gene-info-cards/DDX6
References
PMID: 1579499 by Lu D., et al. Cloning, expression and localization of an RNA helicase gene from a human lymphoid cell line with chromosomal breakpoint 11q23.3.
PMID: 1394235 by Akao Y., et al. The RCK gene associated with t(11;14) translocation is distinct from the MLL/ALL-1 gene with t(4;11) and t(11;19) translocations.