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- Table of Contents
Elongation factor 2 Antibodies
AND EEF2 ELISA kits, Elongation factor 2 Proteins
Many biological assays use antibodies to detect Elongation factor 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Elongation factor 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Elongation factor 2 antibodies...
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EEF2 Infographic by Boster Bio
All EEF2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00830-1
100 μl
Cat # M00830-1
100 μl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1180
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1180
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC1985
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC1985
1 kit, containing two 96-well plates and all necessary reagents
Human, Monkey, Mouse, Rat, Zebrafish
ELISA, IHC, WB
$370
Cat # A00830-1
100 μg/vial
Cat # A00830-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00830-2
100 μg/vial
Cat # M00830-2
100 μg/vial
Human, Monkey, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00830-2
100 μg/vial
Cat # A00830-2
100 μg/vial
EEF2 Overview
Facts about Elongation factor 2.
Elongation factor 2 (EEF2)
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the recently formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA proceed to the P and E sites, respectively.
Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. .
Gene Information
| Human | |
|---|---|
| Gene Name: | EEF2 |
| Uniprot: | P13639 |
| Entrez: | 1938 |
Family
| Belongs to: |
|---|
| TRAFAC class translation factor GTPase superfamily |
Alternative Names
eEF2; eEF-2; EF-2; EF2EEF-2; elongation factor 2; eukaryotic translation elongation factor 2; polypeptidyl-tRNA translocase
Molecular Weight
Mass (kDA):
95.338 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.3 |
| Sequence: | 19; NC_000019.10 (3976056..3985463, complement) |
Subcellular Localizations
Cytoplasm. Nucleus. Phosphorylation by CSK promotes cleavage and SUMOylation-dependent nuclear translocation of the C-terminal cleavage product.
Diseases
- Malignant Neoplasms
- Hypertrophy
- Diphtheria
- Neoplasms
- Hypoxia
- Depressive Disorder
- Ischemia
- Diabetes Mellitus
- Atrophy
- Anoxia
- Tissue Adhesions
- Diabetes Mellitus, Non-insulin-dependent
- Muscular Atrophy
Interacting Proteins
- Akt2
- HSD17B10
Pathways
- Translation
- Cell Death
- Regulation Of Translation
- Cell Cycle
- Localization
- Pathogenesis
- Translational Elongation
- Cell Growth
- Transport
- Energy Homeostasis
- Muscle Atrophy
- Protein Phosphorylation
- Induction Of Apoptosis
PTMs
- Phosphorylation
- Dephosphorylation
- Ribosylation
- Cleavage
- Acetylation
Research Areas
- Core ESC-Like Genes
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EEF2
bosterbio.com/bosterbio-gene-info-cards/EEF2
References
PMID: 2610926 by Rapp G., et al. Complete sequence of the coding region of human elongation factor 2 (EF-2) by enzymatic amplification of cDNA from human ovarian granulosa cells.
PMID: 1596361 by Hanes J., et al. Construction of a plasmid containing the complete coding region of human elongation factor 2.