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- Table of Contents
Fatty acid synthase Antibodies
AND FASN ELISA kits, Fatty acid synthase Proteins
Many biological assays use antibodies to detect Fatty acid synthase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Fatty acid synthase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Fatty acid synthase antibodies...
Designing a Western blot for Fatty acid synthase? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the FASN Western Blot GuideFASN Infographic by Boster Bio
All FASN Products
Product
Figures
Specificity
Applications
Price
Anti-Fatty Acid Synthase/FASN Antibody Picoband®
9 Citations
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # PB9865
100 μg/vial
Cat # PB9865
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00941
100 μl
Cat # M00941
100 μl
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00941-2
20μL, 40μL, 100μL, 200μL
Cat # M00941-2
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$405
Cat # A00941-2
100ul
Cat # A00941-2
100ul
Human
$960
Cat # LS002194
20 µg, 100 µg
Cat # LS002194
20 µg, 100 µg
FASN Overview
Facts about Fatty acid synthase.
Fatty acid synthase (FASN)
Fatty acid synthetase catalyzes the formation of long- chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | FASN |
| Uniprot: | P49327 |
| Entrez: | 2194 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
EC 2.3.1; EC 2.3.1.85; EC 6.3.3.1; FASN; FASshort chain dehydrogenase/reductase family 27X, member 1; Fatty Acid Synthase; MGC14367; MGC15706; OA-519; SDR27X1
Molecular Weight
Mass (kDA):
273.427 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q25.3 |
| Sequence: | 17; NC_000017.11 (82078338..82098303, complement) |
Tissue Specificity
Ubiquitous. Prominent expression in brain, lung, and liver.
Subcellular Localizations
Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Diseases
- Malignant Neoplasms
- Neoplasms
- Obesity
- Carcinoma
- Malignant Neoplasm Of Breast
- Malignant Neoplasm Of Prostate
- Mammary Neoplasms
- Prostatic Neoplasms
- Insulin Resistance
- Steatosis
- Fatty Liver
- Diabetes Mellitus
- Cell Transformation, Neoplastic
Interacting Proteins
- LACC1
Pathways
- Cell Proliferation
- Cell Cycle
- Pathogenesis
- Secretion
- Cell Growth
- Transport
- Cell Death
- Methylation
- Lactation
- Fatty Acid Oxidation
- Translation
- Rna Interference
- Glycolysis
PTMs
- Phosphorylation
- Methylation
- Oxidation
- Cleavage
- Ubiquitination
- Palmitoylation
Research Areas
- Cancer
- Diabetes Research
- Lipid and Metabolism
- Neuroendocrinology
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FASN
bosterbio.com/bosterbio-gene-info-cards/FASN
References
PMID: 7567999 by Jayakumar A., et al. Human fatty acid synthase: properties and molecular cloning.
PMID: 8022791 by Kuhajda F.P., et al. Fatty acid synthesis: a potential selective target for antineoplastic therapy.
2 Publications of Boster Fatty acid synthase Antibodies & ELISA Kits
- PubMed ID: 10.1002/cbin.11490, Fat mass and obesity‐associated protein regulates lipogenesis via m6A modifica...
- PubMed ID: 28443464, Lu C, Ma J, Cai D. Tumour Biol. 2017 Apr;39(4):1010428317697574. doi: 10.1177/10...
*More publications can be found for each product on its corresponding product page