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- Table of Contents
FH Antibodies
AND FH ELISA kits, FH Proteins
Many biological assays use antibodies to detect FH, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FH in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FH antibodies...
Designing a Western blot for FH? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the FH Western Blot GuideFH Infographic by Boster Bio
All FH Products
Product
Figures
Specificity
Applications
Price
Human
IHC, WB
$370
Cat # M01204-1
100 μg/vial
Cat # M01204-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, IHC-F, ICC, WB
$370
Cat # A02097
100 μg/vial
Cat # A02097
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A01259-1
100 μg/vial
Cat # A01259-1
100 μg/vial
Human, Monkey, Mouse, Rat
IHC, WB
$370
Cat # M02097
100 μg/vial
Cat # M02097
100 μg/vial
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01258-1
100 μg/vial
Cat # A01258-1
100 μg/vial
Human, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9181
100 μg/vial
Cat # PB9181
100 μg/vial
Human
Flow Cytometry, IF, ICC, WB
$370
Cat # M01200
100 μg/vial
Cat # M01200
100 μg/vial
Human, Mouse, Rat
IP, IF, ICC, WB
$370
Cat # M02129-1
100 μl/vial
Cat # M02129-1
100 μl/vial
Dog, Human, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$523
Cat # M02097-1
100 µl
Cat # M02097-1
100 µl
Human, Mouse, Rat
IHC, WB
$523
Cat # M01200-2
100 µl
Cat # M01200-2
100 µl
Human, Monkey, Mouse
ELISA, IF, IHC, WB
$380
Cat # M04495-1
100ul
Cat # M04495-1
100ul
Human
ELISA
$480
Cat # EKC1215
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1215
1 kit, containing one 96-well plate and all necessary reagents
FH Overview
Facts about Fumarate hydratase, mitochondrial.
Fumarate hydratase, mitochondrial (FH)
Also acts as a tumor suppressor. .
Gene Information
| Human | |
|---|---|
| Gene Name: | FH |
| Uniprot: | P07954 |
| Entrez: | 2271 |
Family
| Belongs to: |
|---|
| class-II fumarase/aspartase family |
Alternative Names
EC 4.2.1.2; fumarase; fumarate hydratase; fumarate hydratase, mitochondrial; HLRCC; LRCC; MCL; MCUL1
Molecular Weight
Mass (kDA):
54.637 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q43 |
| Sequence: | 1; NC_000001.11 (241497603..241519755, complement) |
Tissue Specificity
Expressed in red blood cells; underexpressed in red blood cells (cytoplasm) of patients with hereditary non- spherocytic hemolytic anemia of unknown etiology.
Subcellular Localizations
[Isoform Mitochondrial]: Mitochondrion.; [Isoform Cytoplasmic]: Cytoplasm, cytosol. Nucleus. Chromosome. Translocates to the nucleus in response to DNA damage: localizes to DNA double-strand breaks (DSBs) following phosphorylation by PRKDC.
Diseases
- Hypercholesterolemia
- Hypercholesterolemia, Familial
- Hyperlipoproteinemia Type Iib
- Malignant Neoplasms
- Neoplasms
- Atherosclerosis
- Familial Hypercholesterolemia - Heterozygous
- Coronary Heart Disease
- Heart Diseases
- Hypertensive Disease
- Kidney Neoplasm
- Cardiovascular Diseases
Interacting Proteins
- H2AFZ
- PIM1
Pathways
- Pathogenesis
- Secretion
- Complement Activation
- Transport
- Excretion
- Localization
- Virulence
- Immune Response
- Cytokinesis
- Cell Differentiation
- Menarche
- Cell Proliferation
- Endocytosis
PTMs
- Cleavage
- Phosphorylation
- Oxidation
- Methylation
- Glycosylation
- Acetylation
- Hydroxylation
Research Areas
- Cell Cycle and Replication
- Core ESC-Like Genes
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FH
bosterbio.com/bosterbio-gene-info-cards/FH
References
PMID: 3828494 by Kinsella B.T., et al. Nucleotide sequence of a cDNA coding for mitochondrial fumarase from human liver.
PMID: 27037871 by Dik E., et al. Human fumarate hydratase is dual localized by an alternative transcription initiation mechanism.
5 Publications of Boster FH Antibodies & ELISA Kits
- PubMed ID: 10.1007/s10753-013-9769-x, Difference in LDL Receptor Feedback Regulation in Macrophages and Vascular Smoot...
- PubMed ID: 10.1007/s00011-009-0052-4, Inflammatory stress increases unmodified LDL uptake via LDL receptor: an alterna...
- PubMed ID: 34151999, Zha K,Ye Q.Golgi a-mannosidase II mediates the formation of vascular smooth musc...
- PubMed ID: 3000101, Neuroprotective Properties of Picroside II in a Rat Model of Focal Cerebral Isch...
- PubMed ID: 21151457, Li Q, Li Z, Xu Xy, Guo Yl, Du F. Int J Mol Sci. 2010 Nov 16;11(11):4580-90. Doi:...
*More publications can be found for each product on its corresponding product page