Low affinity immunoglobulin gamma Fc region receptor II (Fcgr2)

Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor.

Involved in many different effector and regulatory functions such as phagocytosis of antigen-antibody complexes from the circulation and modulation of antibody production by B-cells. Isoform IIB1 and isoform IIB1' form caps but fail to mediate endocytosis or phagocytosis.