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- Table of Contents
HLX Antibodies
AND HLX ELISA kits, HLX Proteins
Many biological assays use antibodies to detect HLX, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HLX in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HLX antibodies...
Designing an IHC experiment for HLX? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the HLX IHC GuideHLX Infographic by Boster Bio
All HLX Products
Product
Figures
Specificity
Applications
Price
HLX Overview
Facts about H2.0-like homeobox protein.
H2.0-like homeobox protein (HLX)
Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as upkeep of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis (By similarity).
. .
Gene Information
| Human | |
|---|---|
| Gene Name: | HLX |
| Uniprot: | Q14774 |
| Entrez: | 3142 |
Family
| Belongs to: |
|---|
| H2.0 homeobox family |
Alternative Names
H2.0 (Drosophila)-like homeo box 1; H2.0-like homeo box 1; H2.0-like homeo box-1; H2.0-like homeobox 1; H2.0-like homeobox protein; H2.0-like homeobox; HB24; HLX1H2.0-like homeobox 1 (Drosophila); Homeobox protein HB24; Homeobox protein HLX1
Molecular Weight
Mass (kDA):
50.789 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q41 |
| Sequence: | 1; NC_000001.11 (220879443..220885059) |
Tissue Specificity
Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.
Subcellular Localizations
Nucleus.
Diseases
- Leukemia
- Childhood Asthma
- Asthma
- Myeloid Leukemia
- Fetal Growth Retardation
- Neoplasms
- Congenital Abnormality
- Leukemia, Myelocytic, Acute
- Tissue Adhesions
- Diaphragmatic Hernia
- Disorder Of Pregnancy
- Congenital Diaphragmatic Hernia
- Hernia
Interacting Proteins
- SUZ12
Pathways
- Cell Differentiation
- Cell Adhesion
- Cell Migration
- Liver Development
- Phagocytosis
- Chromatin Remodeling
- Diaphragm Development
- Cell Proliferation
- Endocytosis
- Localization
- Secretion
- Cell Activation
- Neutrophil Differentiation
PTMs
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HLX
bosterbio.com/bosterbio-gene-info-cards/HLX
References
PMID: 1676597 by Deguchi Y., et al. Cloning of a human homeobox gene that resembles a diverged Drosophila homeobox gene and is expressed in activated lymphocytes.
PMID: 7806220 by Kennedy M.A., et al. Genomic structure, promoter sequence, and revised translation of human homeobox gene HLX1.