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- Table of Contents
IGFBP1 Antibodies
AND IGFBP1 ELISA kits, IGFBP1 Proteins
Many biological assays use antibodies to detect IGFBP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IGFBP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IGFBP1 antibodies...
Designing a Western blot for IGFBP1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the IGFBP1 Western Blot GuideIGFBP1 Infographic by Boster Bio
All IGFBP1 Products
Product
Figures
Specificity
Applications
Price
Human CYR61/CCN1 ELISA Kit PicoKine®
2 Citations
Human
ELISA
$750
Cat # EK1203
96 wells/kit, with removable strips.
Cat # EK1203
96 wells/kit, with removable strips.
Anti-IGFBP1 Antibody Picoband®
1 Citations
Mouse, Rat
IHC, WB, ELISA (Cap)
$370
Cat # A00922-1
100 μg/vial
Cat # A00922-1
100 μg/vial
Anti-ASK1/MAP3K5 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00929-3
100 μg/vial
Cat # A00929-3
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00924-2
100 μg/vial
Cat # A00924-2
100 μg/vial
Anti-ARF6 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A00927-2
100 μg/vial
Cat # A00927-2
100 μg/vial
Anti-CCN1/CYR61 Antibody Picoband®
1 Citations
Human, Mouse, Rat
IHC, WB
$370
Cat # PB9549
100 μg/vial
Cat # PB9549
100 μg/vial
Anti-IGFBP1 Rabbit Monoclonal Antibody
1 Citations
Human, Mouse, Rat
WB
$370
Cat # M00922-1
100 μl/vial
Cat # M00922-1
100 μl/vial
IGFBP1 Overview
Facts about Insulin-like growth factor-binding protein 1.
Insulin-like growth factor-binding protein 1 (IGFBP1)
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell membranes.
Promotes cell migration. .
Gene Information
| Human | |
|---|---|
| Gene Name: | IGFBP1 |
| Uniprot: | P08833 |
| Entrez: | 3484 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
alpha-pregnancy-associated endometrial globulin; amniotic fluid binding protein; binding protein-25; binding protein-26; binding protein-28; growth hormone independent-binding protein; hIGFBP-1; IBP1; IBP-1; IGF-binding protein 1; IGFBP1; IGFBP-1; IGF-BP25; insulin-like growth factor binding protein 1; insulin-like growth factor-binding protein 1; Placental protein 12; PP12AFBP
Molecular Weight
Mass (kDA):
27.904 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7p12.3 |
| Sequence: | 7; NC_000007.14 (45888488..45893660) |
Subcellular Localizations
Secreted.
Diseases
- Malignant Neoplasms
- Endometrial Polyp
- Diabetes Mellitus
- Insulin Resistance
- Neoplasms
- Obesity
- Insulin Sensitivity
- Diabetes Mellitus, Non-insulin-dependent
- Mammary Neoplasms
- Malignant Neoplasm Of Breast
- Fetal Growth Retardation
- Liver Carcinoma
- Endometriosis, Site Unspecified
Interacting Proteins
- FAM20C
- IGF1
Pathways
- Secretion
- Decidualization
- Pathogenesis
- Localization
- Glucose Homeostasis
- Cell Proliferation
- Cell Growth
- Angiogenesis
- Embryo Implantation
- Proteolysis
- Methylation
- Insulin Secretion
- Fertilization
PTMs
- Phosphorylation
- Methylation
- Cleavage
- Acetylation
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IGFBP1
bosterbio.com/bosterbio-gene-info-cards/IGFBP1
References
PMID: 2461294 by Brinkman A., et al. Isolation and characterization of a cDNA encoding the low molecular weight insulin-like growth factor binding protein (IBP-1).
PMID: 2454104 by Brewer M.T., et al. Cloning, characterization, and expression of a human insulin-like growth factor binding protein.
12 Publications of Boster IGFBP1 Antibodies & ELISA Kits
- PubMed ID: 10.1152/ajpendo.00323.2019, DPP4 deletion in adipose tissue improves hepatic insulin sensitivity in diet-ind...
- PubMed ID: 10.1093/molehr/gaw042, Decreased expression of NR4A nuclear receptors in adenomyosis impairs endometria...
- PubMed ID: 10.1042/CS20180474, Novel treatment avenues for uterine leiomyoma: a new implication for endothelin?
- PubMed ID: 10.1038/cgt.2016.27, MicroRNA-145 functions as a tumor suppressor by targeting matrix metalloproteina...
- PubMed ID: 10.1016/j.bbrc.2013.02.078, Krüppel-like factor 12 negatively regulates human endometrial stromal cell deci...
- PubMed ID: 10.1016/j.bbrc.2010.07.032, Insulin-like growth factor binding protein-1 levels are increased in patients wi...
- PubMed ID: 10.1016/j.bbmt.2018.01.027, Inflammation-Associated Cytokines IGFBP1 and RANTES Impair the Megakaryocytic Po...
- PubMed ID: 10.1007/s11596-019-2134-z, Activation of Uterine Smad3 Pathway Is Crucial for Embryo Implantation
- PubMed ID: 23458459 , Krüppel-like factor 12 negatively regulates human endometrial stromal cell deci...
- PubMed ID: 20637724, Insulin-like growth factor binding protein-1 levels are increased in patients wi...
- PubMed ID: 24548465, Hepatic Hedgehog signaling contributes to the regulation of IGF1 and IGFBP1 seru...
- PubMed ID: 23748030, Zhang S, Zhao Y, Hu X, Liu Z, Chen X, Chen X, Du J. Mol Cell Endocrinol. 2013 Au...
*More publications can be found for each product on its corresponding product page