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- Table of Contents
MAP1B Antibodies
AND MAP1B ELISA kits, MAP1B Proteins
Many biological assays use antibodies to detect MAP1B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MAP1B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MAP1B antibodies...
Designing a Western blot for MAP1B? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MAP1B Western Blot GuideDesigning an IHC experiment for MAP1B? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the MAP1B IHC GuideMAP1B Infographic by Boster Bio
All MAP1B Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IP, IF, ICC, WB
$370
Cat # M01524
100 μl
Cat # M01524
100 μl
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01543-1
100 μl
Cat # M01543-1
100 μl
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A01760-1
100 μg/vial
Cat # A01760-1
100 μg/vial
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # M01543
100 μl
Cat # M01543
100 μl
Human
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01551-4
100 μl/vial
Cat # M01551-4
100 μl/vial
Human, Mouse
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01551-3
100 μl/vial
Cat # M01551-3
100 μl/vial
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M01525
100 μl/vial
Cat # M01525
100 μl/vial
MAP1B Overview
Facts about Microtubule-associated protein 1B.
Microtubule-associated protein 1B (MAP1B)
Facilitates tyrosination of alpha-tubulin in neuronal microtubules (By similarity). Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension.
Possibly MAP1B binds to at least two tubulin subunits from the polymer, and this bridging of subunits may be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing.
Gene Information
| Human | |
|---|---|
| Gene Name: | MAP1B |
| Uniprot: | P46821 |
| Entrez: | 4131 |
Family
| Belongs to: |
|---|
| MAP1 family |
Alternative Names
DKFZp686E1099; DKFZp686F1345; FLJ38954; FUTSCH; MAP-1B; MAP5; microtubule-associated protein 1B
Molecular Weight
Mass (kDA):
270.634 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q13.2 |
| Sequence: | 5; NC_000005.10 (72107475..72209565) |
Subcellular Localizations
Cytoplasm, cytoskeleton. Cytoplasm. Cell junction, synapse. Cell projection, dendritic spine. Colocalizes with DAPK1 in the microtubules and cortical actin fibers.; [MAP1 light chain LC1]: Cytoplasm.
Diseases
- Nervousness
- Alzheimer's Disease
- Neurodegenerative Disorders
- Nerve Degeneration
- Atrophy
- Muscular Atrophy
- Spinal Muscular Atrophy
- Fragile X Syndrome
- Neuroblastoma
- Neoplasms
- Neurofibrillary Tangles
Interacting Proteins
- GAN
- KIRREL3
- LRRK2
- TP53
Pathways
- Localization
- Brain Development
- Transport
- Regeneration
- Cell Death
- Translation
- Cell Differentiation
- Pathogenesis
- Neurogenesis
- Hyperphosphorylation
- Aging
- Autophagy
- Axon Extension
PTMs
- Phosphorylation
- Dephosphorylation
- Cleavage
- Acetylation
- Methylation
- Nitrosylation
Research Areas
- Cell Biology
- Cellular Markers
- MAP Kinase Signaling
- Neuronal Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAP1B
bosterbio.com/bosterbio-gene-info-cards/MAP1B
References
PMID: 7806212 by Lien L.L., et al. Cloning of human microtubule-associated protein 1B and the identification of a related gene on chromosome 15.
PMID: 12684070 by Dergunova L.V., et al. Hmob3 brain-specific sequence is a part of phylogenetically conserved human MAP1B gene 3'-untranslated region.
5 Publications of Boster MAP1B Antibodies & ELISA Kits
- PubMed ID: -, Zhang Tao,Xiaoqing Zhou,Yan Zhang,Wenfeng Pu,Yi Yang,Fuxia Wei,Qian Zhou,Lin Zha...
- PubMed ID: -, Xiaodong Zhou, Hongsheng Ouyang, Daxin Pang et al. Pathological Alterations in t...
- PubMed ID: 33285262, Wu K,Yue J,Shen K,He J,Zhu G,Liu S,Zhang C,Yang H. Increased Expression of Fibro...
- PubMed ID: 28031531, Overendocytosis of superparamagnetic iron oxide particles increases apoptosis an...
- PubMed ID: 29066806, Dai L, Chen X, Lu X, Wang F, Zhan Y, Song G, Hu T, Xia C, Zhang B. Sci Rep. 2017...
*More publications can be found for each product on its corresponding product page