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- Table of Contents
2 Citations 7 Q&As
7 Citations 1 Q&As
1 Citations
Facts about Neprilysin.
Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:15283675). Involved in the degradation of atrial natriuretic factor (ANF) (PubMed:2531377, PubMed:2972276).
Human | |
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Gene Name: | MME |
Uniprot: | P08473 |
Entrez: | 4311 |
Belongs to: |
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peptidase M13 family |
Atriopeptidase; CALLA; CALLAmembrane metallo-endopeptidase (neutral endopeptidase, enkephalinase); CD10 antigen; CD10; CD10); CD10membrane metallo-endopeptidase variant 1; Common acute lymphocytic leukemia antigen; DKFZp686O16152; EC 3.4.24; EC 3.4.24.11; Enkephalinase; EPN; Leu-19; membrane metallo-endopeptidase variant 2; membrane metallo-endopeptidase; MGC126681; MGC126707; MME; NEPmembrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA; Neprilysin; Neutral Endopeptidase 24.11; Neutral endopeptidase; NKH1; SFE; Skin fibroblast elastase
Mass (kDA):
85.514 kDA
Human | |
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Location: | 3q25.2 |
Sequence: | 3; NC_000003.12 (155024124..155183729) |
Cell membrane; Single-pass type II membrane protein.
PMID: 2971756 by Letarte M., et al. Common acute lymphocytic leukemia antigen is identical to neutral endopeptidase.
PMID: 2968607 by Shipp M.A., et al. Molecular cloning of the common acute lymphoblastic leukemia antigen (CALLA) identifies a type II integral membrane protein.
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