Nucleobindin-2 Antibodies

AND NUCB2 ELISA kits, Nucleobindin-2 Proteins

Many biological assays use antibodies to detect Nucleobindin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nucleobindin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nucleobindin-2 antibodies...

We validate the specificity of these antibodies to Nucleobindin-2 by testing them on tissues known to express NUCB2 positively and negatively. Browse below to find the NUCB2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Nucleobindin-2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the NUCB2 IHC Guide

NUCB2 Infographic by Boster Bio

All NUCB2 Products

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Specificity

Applications

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Human Nesfatin-1/NUCB2/Nucleobindin-2 ELISA Kit PicoKine®

10 Citations

Human

ELISA

$499
Cat # EK1138
96 wells/kit, with removable strips.

Anti-Nucleobindin 2/NUCB2 Antibody Picoband®

IHC analysis of Nucleobindin 2 using anti-Nucleobindin 2 antibody (PB9876)

Western blot analysis of Nucleobindin 2 using anti-Nucleobindin 2 antibody (PB9876)

Mouse, Rat

ELISA, IHC, WB

$370
Cat # PB9876
100 μg/vial

Anti-Nucleobindin-2 NUCB2 Antibody

Western blot analysis of Nucleobindin-2 in rat brain tissue lysate with Nucleobindin-2 antibody at (A) 0

Immunohistochemistry of Nucleobindin-2 in rat brain tissue with Nucleobindin-2 antibody at 2

Immunofluorescence of Nucleobindin-2 in rat brain tissue with Nucleobindin-2 antibody at 20 μg/ml

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A02400
0.1 mg

Mouse Nesfatin-1/Nucleobindin-2 Recombinant Protein

SDS-PAGE

$250
Cat # PROTP81117
Starting from 20ug

NUCB2 Overview

Facts about Nucleobindin-2.

NUCB2 3D structure. Source: alphafold

Nucleobindin-2 (NUCB2)

Calcium-binding protein. May have a role in calcium homeostasis.

Gene Information

Human
Gene Name:	NUCB2
Uniprot:	P80303
Entrez:	4925

Family

Belongs to:

nucleobindin family

Alternative Names

DNA-binding protein NEFA; NEFA; NEFAGastric cancer antigen Zg4; Nesfatin1; Nesfatin-1; NUCB2; nucleobindin 2; Nucleobindin-2; nucleobinding 2

Molecular Weight

Mass (kDA):
50.223 kDA

Genomic Context


Human

Location:	11p15.1
Sequence:	11; NC_000011.10 (17260337..17349980)

Tissue Specificity

Predominantly expressed in spleen, testis and normal stomach.

Subcellular Localizations

Golgi apparatus. Membrane; Peripheral membrane protein. Cytoplasm. Secreted. Endoplasmic reticulum. Nucleus envelope. Golgi retention is mediated by its N-terminal region.; [Nesfatin-1]: Secreted.

Diseases

Obesity
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Nervousness
Disease Of Adrenal Medulla
Pituitary Diseases
Stress, Psychological
Malignant Neoplasms
Stomach Neoplasms
Neoplasms
Anxiety Disorders
Mental Disorders

Diabetes Mellitus, Insulin-dependent
Insulin Resistance
Metabolic Diseases
Malignant Neoplasm Of Stomach
Neoplasm Metastasis
Metastatic Malignant Neoplasm To The Lymph Node
Malignant Neoplasm Of Breast

Interacting Proteins

GADD45A

Pathways

Secretion
Energy Homeostasis
Insulin Secretion
Localization
Feeding Behavior
Pathogenesis
Transport
Immune Response
Inflammatory Response
Glucose Homeostasis
Innate Immune Response
Testosterone Secretion
Regulation Of Feeding Behavior

Exocytosis
Glucagon Secretion
Follicle-stimulating Hormone Secretion
Hormone Secretion
Cell Proliferation
Blood Vessel Development
Induction Of Apoptosis

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NUCB2

References

PMID: 7811391 by Barnikol-Watanabe S., et al. Human protein NEFA, a novel DNA binding/EF-hand/leucine zipper protein. Molecular cloning and sequence analysis of the cDNA, isolation and characterization of the protein.

PMID: 9639681 by Deangelis M.M., et al. Assembly of a high-resolution map of the Acadian Usher syndrome region and localization of the nuclear EF-hand acidic gene.

10 Publications of Boster Nucleobindin-2 Antibodies & ELISA Kits

PubMed ID: 10.6515/ACS.201809_34(5).20180423A, The Relationship between Nesfatin-1 Levels and SYNTAX Score in Patients with Non...
PubMed ID: 10.5603/kp.a2017.0210, Nesfatin-1 levels in patients with slow coronary flow.
PubMed ID: 10.14715/cmb/2018.64.10.21, Nesfatin-1 and irisin levels in response to the soccer matches performed in morn...
PubMed ID: 10.1177/2058739218824236, Changes in ghrelin and nesfatin-1 in children with growth hormone deficiency tre...
PubMed ID: 10.1136/postgradmedj-2020-139227, Increased serum nesfatin-1 levels in patients with inflammatory bowel diseases
PubMed ID: 10.1016/j.peptides.2019.04.003, Nesfatin-1: A novel regulatory peptide associated with acute myocardial infarcti...
PubMed ID: 30271088, The Relationship between Nesfatin-1 Levels and SYNTAX Score in Patients with Non...
PubMed ID: 29714458, Increased concentrations of serum nesfatin-1 levels in childhood with idiopathic...
PubMed ID: 29472736, Algul S, Ozdenk C, Ozcelik O. Biol Sport. 2017 Dec;34(4):339-344. doi: 10.5114/b...
PubMed ID: 25833360, ??atl?? G, An??k A, K??me T, ??alan ??g, D??ndar Bn, B??ber E, Abac?? A. J Endoc...

*More publications can be found for each product on its corresponding product page