Pdcd1lg2 Antibodies

AND Pdcd1lg2 ELISA kits, Pdcd1lg2 Proteins

Many biological assays use antibodies to detect Pdcd1lg2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Pdcd1lg2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Pdcd1lg2 antibodies...

We validate the specificity of these antibodies to Pdcd1lg2 by testing them on tissues known to express Pdcd1lg2 positively and negatively. Browse below to find the Pdcd1lg2 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Pdcd1lg2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the PDCD1LG2 Western Blot Guide

Designing an IHC experiment for Pdcd1lg2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the PDCD1LG2 IHC Guide

Pdcd1lg2 Infographic by Boster Bio

All Pdcd1lg2 Products

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Product

Figures

Specificity

Applications

Price

Human PD-L2/B7-DC ELISA Kit PicoKine®

Human

ELISA

$499
Cat # EK1447
96 wells/kit, with removable strips.

Anti-B7 DC/PDCD1LG2 Antibody Picoband®

Western blot analysis of B7 DC using anti-B7 DC antibody (PB10010)

Human

$370
Cat # PB10010
100 μg/vial

Anti-PD-L2 PDCD1LG2 Antibody

Western Blot Validation in Human Raji Cell Lysate
Loading: 15 μg of lysates per lane

KO Validation in HeLa Cells
Loading: 15 μg of HeLa WT cell lysates or PD-L2 KO cell lysates

Human, Mouse

ELISA, IF, IHC-P, WB

$481
Cat # A03295
0.1 mg

Anti-PDL2 PDCD1LG2 Monoclonal Antibody [4E10]

Western blot analysis of PD-L2 in overexpressing HEK293 cells PD-L2 antibody at 0

Immunocytochemistry of PD-L2 in transfected HEK293 cells with PD-L2 antibody at 5 μg/mL

Immunofluorescence of PD-L2 in transfected HEK293 cells with PD-L2 antibody at 20 μg/mL

Human

ELISA, Flow Cytometry, IF, IHC-P, ICC, WB

$481
Cat # M03295
0.1 mg

Anti-PDCD1LG2 Antibody (N-term)

Immunohistochemical analysis of PDL-2 in untransfected(left) or transfected(right) with 293T cell sections

Human

IHC-P, WB

$299
Cat # M03295-1
50 µl

PD L2 (PDCD1LG2) (NM_025239) Human Over-expression Lysate

Human

$628
Cat # LS080380
20 µg, 100 µg

Human PD-L2/B7-DC Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ9BQ51
Starting from 10ug

Pdcd1lg2 Overview

Facts about Programmed cell death 1 ligand 2.

Programmed cell death 1 ligand 2 (Pdcd1lg2)

Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent method. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

Gene Information

Mouse
Gene Name:	Pdcd1lg2
Uniprot:	Q9WUL5
Entrez:	58205

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

B7-DC; bA574F11.2; Btdc; Butyrophilin B7-DC; Butyrophilin-like Protein; CD273 antigen; CD273; CD273PD-1 ligand 2; MGC142240; PD-1-ligand 2; PDCD1L2MGC142238; PDCD1LG2; PDL2; PD-L2; PDL2B7DC; PD-L2PDCD1 ligand 2; programmed cell death 1 ligand 2; Programmed death ligand 2

Molecular Weight

Mass (kDA):
27.82 kDA

Genomic Context


Mouse

Location:	19\|19 C1
Sequence:	19;

Tissue Specificity

Expressed in immature and mature bone marrow- derived dendritic cells and splenic dendritic cells. Highly expressed in placenta, liver and weakly expressed in heart, spleen, lymph nodes and thymus. Also expressed in some tumor cell lines of lymphoid origin.

Diseases

Neoplasms
Autoimmune Reaction
Malignant Neoplasms
Inflammation
Autoimmune Diseases
Autoimmunity
Asthma
Hepatitis
Infective Disorder
Decreased Immunologic Activity [pe]
Virus Diseases
Diabetes Mellitus
Lupus Erythematosus, Systemic

Chronic Infectious Disease
Experimental Autoimmune Encephalomyelitis
Encephalomyelitis
Hepatitis, Chronic
Diabetes Mellitus, Insulin-dependent
Hiv Infections
Hepatitis B

Pathways

Cytokine Production
Cell Activation
T Cell Activation
Cell Proliferation
Immune Response
T Cell Proliferation
Cell Death
Programmed Cell Death
Secretion
Pathogenesis
Sensitization
Cytokine Secretion
Hypersensitivity

Cell Differentiation
Tolerance Induction
Cell Maturation
Regulation Of T Cell Activation
Interleukin-2 Production
Macrophage Activation
T Cell Cytokine Production

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Pdcd1lg2

References

PMID: 11283156 by Tseng S.-Y., et al. B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells.

PMID: 11224527 by Latchman Y., et al. PD-L2 is a second ligand for PD-1 and inhibits T cell activation.