This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
RANBP2 Antibodies
AND RANBP2 ELISA kits, RANBP2 Proteins
Many biological assays use antibodies to detect RANBP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RANBP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RANBP2 antibodies...
Designing a Western blot for RANBP2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the RANBP2 Western Blot GuideDesigning an IHC experiment for RANBP2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the RANBP2 IHC GuideRANBP2 Infographic by Boster Bio
All RANBP2 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00981-1
100 µg/vial
Cat # A00981-1
100 µg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02901-1
100 µg/vial
Cat # A02901-1
100 µg/vial
Human
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A02900-3
100 μg/vial
Cat # A02900-3
100 μg/vial
RANBP2 Overview
Facts about E3 SUMO-protein ligase RanBP2.
E3 SUMO-protein ligase RanBP2 (RANBP2)
E3 SUMO-protein ligase which Eases SUMO1 and SUMO2 conjugation by UBE2I (PubMed:11792325, PubMed:12032081, PubMed:15378033, PubMed:22194619, PubMed:15931224).
Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import through the F-G repeat-containing domain which acts as a docking site for substrates (PubMed:7775481).May bind DNA (PubMed:7775481). Component of the nuclear export pathway (PubMed:10078529).
Gene Information
| Human | |
|---|---|
| Gene Name: | RANBP2 |
| Uniprot: | P49792 |
| Entrez: | 5903 |
Family
| Belongs to: |
|---|
| RanBP2 E3 ligase family |
Alternative Names
ANE1; E3 SUMO-protein ligase RanBP2; EC 5.2.1.8; Nuclear pore complex protein Nup358; nucleoporin 358; Nucleoporin Nup358; NUP358TRP2; p270; RAN binding protein 2; Ran-binding protein 2; RanBP2; transformation-related protein 2,358 kDa nucleoporin; TRP1
Molecular Weight
Mass (kDA):
358.199 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q13 |
| Sequence: | 2; NC_000002.12 (108719446..108785809) |
Subcellular Localizations
Nucleus. Nucleus membrane. Nucleus, nuclear pore complex. Nucleus envelope. Detected in diffuse and discrete intranuclear foci (PubMed:11839768). Cytoplasmic filaments (PubMed:7775481).
Diseases
- Virus Diseases
- Encephalopathies
- Malignant Neoplasms
- Leukoencephalitis, Acute Hemorrhagic
- Neoplasms
- Infective Disorder
- Hiv Infections
- Immunologic Deficiency Syndromes
- Comatose
- Adenocarcinoma
- Influenza
- Haploinsufficiency
Interacting Proteins
- BICD2
- ERBB2
- PDLIM3
- PRKN
- RAN
- UBE2I
Pathways
- Transport
- Localization
- Nuclear Import
- Nucleocytoplasmic Transport
- Nuclear Export
- Conjugation
- Protein Import
- Mitosis
- Nuclear Transport
- Cell Cycle
- Interphase
- Anaphase
- Spindle Assembly
PTMs
- Sumoylation
- Phosphorylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RANBP2
bosterbio.com/bosterbio-gene-info-cards/RANBP2
References
PMID: 7775481 by Wu J., et al. Nup358, a cytoplasmically exposed nucleoporin with peptide repeats, Ran-GTP binding sites, zinc fingers, a cyclophilin A homologous domain, and a leucine-rich region.
PMID: 7603572 by Yokoyama N., et al. A giant nucleopore protein that binds Ran/TC4.