SOD2 Antibodies

Superoxide dismutase [Mn], mitochondrial (SOD2)

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. .

Gene Information

Human
Gene Name:	SOD2
Uniprot:	P04179
Entrez:	6648

Family

Belongs to:
iron/manganese superoxide dismutase family

Alternative Names

EC 1.15.1.1; indophenoloxidase B; IPOB; IPO-B; manganese-containing superoxide dismutase; mangano-superoxide dismutase; Mn SOD; Mn superoxide dismutase; MnSOD; MVCD6; SOD, Mitochodrial; SOD2; superoxide dismutase [Mn], mitochondrial; superoxide dismutase 2, mitochondrial

Molecular Weight

Mass (kDA):
24.75 kDA

Genomic Context

Human
Location:	6q25.3
Sequence:	6; NC_000006.12 (159669069..159762281, complement)

Subcellular Localizations

Mitochondrion matrix.

Diseases

• Malignant Neoplasms
• Neoplasms
• Inflammation
• Diabetes Mellitus
• Nerve Degeneration
• Carcinoma
• Mammary Neoplasms
• Malignant Neoplasm Of Breast
• Neurodegenerative Disorders
• Ischemia
• Hypertensive Disease
• Parkinson Disease
• Hypoxia

• Malignant Paraganglionic Neoplasm
• Sclerosis
• Neoplasm Metastasis
• Carcinogenesis
• Mitochondrial Diseases
• Cell Transformation, Neoplastic
• Diabetes Mellitus, Non-insulin-dependent

Pathways

• Cell Death
• Aging
• Pathogenesis
• Localization
• Transport
• Cell Proliferation
• Cell Cycle
• Dna Repair
• Oxidative Phosphorylation
• Senescence
• Electron Transport
• Response To Oxidative Stress
• Cell Growth

• Electron Transport Chain
• Neuroprotection
• Angiogenesis
• Immune Response
• Inflammatory Response
• Methylation
• Secretion

PTMs

• Phosphorylation
• Oxidation
• Reduction
• Cleavage
• Methylation
• Nitration
• Acetylation
• Dephosphorylation

• Deacetylation
• Glycosylation
• Demethylation
• Nitrosylation
• Ubiquitination
• Deamination
• Prenylation
• Biotinylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SOD2

Boster Bio Anti-SOD2 Marker and Total Superoxide Dismutase Assay Kit

You've come to the right place in the event you're seeking information about the Boster Bio Anti SOD2 Marker or Total Superoxide Dismutase Kit. Read on to discover how to use the SOD2 marker in your experiments. It can also be used to determine the species that are at greatest risk of suffering from SOD2 damage and which treatments are most effective.

Boster Bio Anti-SOD2 Marker

The Boster Bio Anti-SOD2 Markers provide a specific and high-affinity antibody that reacts with human SOD2 protein. The Boster Bio Anti-SOD2 Marker is supplied in PBS that contains 0.09 percent sodium azide. It is extracted using a protein G column. The Boster Bio AntisOD2 Marker is a product against His-tagged SOD2 proteins and is approved for use in numerous applications such as Flow Cytometry. The antibodies can be utilized in many protocols and assays such as Western Blot analysis as well as flow Cytometry. Boster's Quality Guarantee covers all of its products. Boster is continuously expanding its product offerings every month.

Natural products are generally safe and effective in moderate doses. But it is important to recognize that SOD is present in under-utilized plants and have the pharmacological potency of synthetic SOD. Below is a discussion of the potential of SOD in these plants and the Boster Bio AntisOD2 marker. The safety and effectiveness of the product will be discussed in more detail.

Boster Bio Total Superoxide Dismutase Assay Kit

The Boster Bio Total Superoxide Dioxididase Assay Kit is an excellent choice for scientists who need an accurate, quick method to measure SOD levels in various samples. It comes with many high-quality antibodies validated for ELISA, ICC, and WB. The Boster Bio AntisOD3 Antibody is compatible for human, mouse, and rat samples.

The MBS7608050 microwell strip-plate ELISA kit is used to test the activity of SOD in biological samples. The kit detects interactions between SOD and antibodies and measures SOD activity in different samples. The kit is also compatible with undiluted body fluids tissues homogenates and secretions. This kit comes with a high-quality standard to ensure reproducibility.

The Boster Bio Total Superoxide Dismutidase Assay Kit uses sandwich enzyme-linked immunosorbent technology. Pre-coated capture antibodies were positioned on plates that had 96 wells. Each well was then filled with a biotin conjugated antibody. The wells were then stuffed with test samples and standards. Unbound conjugates were removed by using wash buffer. TMB substrates were used to illustrate the HRP enzyme process. The intensity of yellow was proportional to the amount of sample captured on the plate.

The SOD2 Marker has many advantages

There are numerous advantages to using the SOD2 Marker. The enzyme is extremely effective in reducing the production of reactive oxygen species. The SOD2 protein is found on cell membranes. It also assists in maintaining the balance of redox within the body. However the SOD2 marker is not effective in all cancers. The results of a small study conducted on a small group of patients with colorectal cancer reveal that the SOD2 marker isn't 100% precise in certain cases. The results of this study indicate that cancer patients who carry the SOD2 gene have higher levels of SOD2 than those who didn't.

Studies have shown that SOD2 expression is associated with poor outcomes in a variety of kinds of cancers, including colorectal, lung and oral. SOD2 can be used to detect cancers in the early stages, if SOD2 levels are low. The SOD2 marker is also helpful in determining the stage IIIB of squamous cell carcinoma. The SOD2 marker can be used to determine which patients are susceptible to certain types of cancer and which treatment may be most effective.

The SOD2 Marker has been shown to be an effective instrument for early detection of cervical cancer. It is a crucial part of the comprehensive screening program for cervical cancer. This biomarker may assist doctors in the diagnosis and treatment of women suffering from cancer. However, the sample size was insignificant, so further studies are required to confirm the connection. It is also important to keep in mind that cancer patients with high levels SOD2 expression may be more susceptible to the recurrence of cancer or death than patients with lower levels.

Researchers have discovered that a unique SOD-boosting supplement may be the best method to safeguard yourself from free radicals. Superoxide dismutase is a powerful antioxidant enzyme that is found in every cell in the body. Its presence in the body can help reduce the effects of oxidative stress on biological systemslike the heart. It also helps to reduce inflammation in the internal organs and arthritis pain. These conditions can be avoided by ensuring that the SOD2 Marker is used regularly.

Thyroid tissue produces more SOD3 than normal tissue. TSH stimulation also triggers cAMP -PKA signal transduction and PLC -Ca2+ sign transduction. Thyrocyte proliferation is influenced by an increase in Sod3 gene synthesis. Additionally, SOD3 levels are increased in patients with thyroid cancer, which is characterized by the loss of differentiation markers.

The SOD2 marker can be used to detect SOD2 gene variations. Researchers have identified the three common SOD2 haplotypes as well as six diplotypes. Each of the six diplotypes was assessed separately by researchers. All six diplotypes had no variations in CSF or IC volumes. The TT-AA Val diplotype had the lowest CSF and IC volumes. In contrast, the diplotype TG-AA-Val had the highest CSF and IC volumes.