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- Table of Contents
UGT1A6 Antibodies
AND UGT1A6 ELISA kits, UGT1A6 Proteins
Many biological assays use antibodies to detect UGT1A6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UGT1A6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UGT1A6 antibodies...
Designing a Western blot for UGT1A6? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the UGT1A6 Western Blot GuideUGT1A6 Infographic by Boster Bio
All UGT1A6 Products
Product
Figures
Specificity
Applications
Price
Anti-ARG2 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02244
100 μg/vial
Cat # A02244
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02244-1
100 μg/vial
Cat # A02244-1
100 μg/vial
Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A02239-2
100 μg/vial
Cat # A02239-2
100 μg/vial
UGT1A6 Overview
Facts about UDP-glucuronosyltransferase 1-6.
UDP-glucuronosyltransferase 1-6 (UGT1A6)
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols.
Isoform 3 lacks transferase activity but acts as a negative regulator of isoform 1 (By similarity). .
Gene Information
| Human | |
|---|---|
| Gene Name: | UGT1A6 |
| Uniprot: | P19224 |
| Entrez: | 54578 |
Family
| Belongs to: |
|---|
| UDP-glycosyltransferase family |
Alternative Names
GNT1UDPGT 1-6; HLUGP; HLUGP1; MGC29860; Phenol-metabolizing UDP-glucuronosyltransferase; UDP glucuronosyltransferase 1 family, polypeptide A6; UDP glycosyltransferase 1 family, polypeptide A6; UDP-glucuronosyltransferase 1 family polypeptide A6s; UDP-glucuronosyltransferase 1-6; UDP-glucuronosyltransferase 1A6; UDP-glucuronosyltransferase 1-F; UDPGT; UGT1; UGT1*6; UGT1.6; UGT1-06; UGT1A6S; UGT-1F; UGT1FEC 2.4.1.17
Molecular Weight
Mass (kDA):
60.751 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q37.1 |
| Sequence: | 2; NC_000002.12 (233691670..233773300) |
Tissue Specificity
Expressed in skin. Isoforms 1 and 3 are expressed in kidney and liver. Isoform 1 but not isoform 2 is expressed in colon, esophagus and small intestine.
Subcellular Localizations
Microsome. Endoplasmic reticulum membrane; Single-pass membrane protein.
Diseases
- Malignant Neoplasms
- Carcinoma
- Neoplasms
- Malignant Tumor Of Colon
- Liver Carcinoma
- Carcinogenesis
- Malignant Neoplasm Of Breast
- Dysequilibrium Syndrome
- Liver Neoplasms, Experimental
- Gilbert Disease (disorder)
- Colonic Neoplasms
- Adenoma
- Liver Neoplasms
Pathways
- Conjugation
- Excretion
- Transport
- Reverse Transcription
- Sulfation
- Localization
- Xenobiotic Glucuronidation
- Intestinal Absorption
- Translation
- Cell Differentiation
- Acyl Glucuronidation
- Protein Oxidation
- Membrane Assembly
PTMs
- Reduction
- Hydroxylation
- Oxidation
Research Areas
- Cancer
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UGT1A6
bosterbio.com/bosterbio-gene-info-cards/UGT1A6
References
PMID: 1339448 by Ritter J.K., et al. A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini.
PMID: 3141926 by Harding D., et al. Cloning and substrate specificity of a human phenol UDP- glucuronosyltransferase expressed in COS-7 cells.