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- Table of Contents
VCAM1 Antibodies
AND VCAM1 ELISA kits, VCAM1 Proteins
Many biological assays use antibodies to detect VCAM1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with VCAM1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop VCAM1 antibodies...
Designing a Western blot for VCAM1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the VCAM1 Western Blot GuideVCAM1 Infographic by Boster Bio
All VCAM1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01199-1
100 μl
Cat # M01199-1
100 μl
Human
ELISA
$500
Cat # EZ0537
For 5 plates, 96 wells each
Cat # EZ0537
For 5 plates, 96 wells each
Mouse
ELISA
$500
Cat # EZ0538
For 5 plates, 96 wells each
Cat # EZ0538
For 5 plates, 96 wells each
Human, Mouse, Rat
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01199-3
100 μg
Cat # M01199-3
100 μg
VCAM1 Overview
Facts about Vascular cell adhesion protein 1.
Vascular cell adhesion protein 1 (VCAM1)
Significant in cell-cell recognition. Appears to work in leukocyte-endothelial cell adhesion.
Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
Gene Information
| Human | |
|---|---|
| Gene Name: | VCAM1 |
| Uniprot: | P19320 |
| Entrez: | 7412 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CD106 antigen; CD106; DKFZp779G2333; INCAM-100; L1CAM; MGC99561; vascular cell adhesion molecule 1; vascular cell adhesion protein 1; V-CAM 1; VCAM1; VCAM-1
Molecular Weight
Mass (kDA):
81.276 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p21.2 |
| Sequence: | 1; NC_000001.11 (100719640..100739045) |
Tissue Specificity
Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue.
Subcellular Localizations
Membrane; Single-pass type I membrane protein.
Diseases
- Tissue Adhesions
- Inflammation
- Atherosclerosis
- Neoplasms
- Malignant Neoplasms
- Cardiovascular Diseases
- Neoplasm Metastasis
- Carcinoma
- Cerebrovascular Accident
- Diabetes Mellitus
- Tumor Angiogenesis
- Inflammatory Response
Pathways
- Cell Adhesion
- Pathogenesis
- Immune Response
- Inflammatory Response
- Angiogenesis
- Cell Activation
- Cell Proliferation
- Secretion
- Endothelial Cell Activation
- Cell Cycle
- Vasculogenesis
- Cell Division
- Transport
PTMs
- Phosphorylation
- Reduction
Research Areas
- Cancer
- Mesenchymal Stem Cell Markers
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VCAM1
bosterbio.com/bosterbio-gene-info-cards/VCAM1
References
PMID: 2688898 by Osborn L., et al. Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes.
PMID: 1699207 by Polte T., et al. Full length vascular cell adhesion molecule 1 (VCAM-1).
76 Publications of Boster VCAM1 Antibodies & ELISA Kits
- PubMed ID: PMID:31105824, Vaccarin prevents ox-LDL-induced HUVEC EndMT, inflammation and apoptosis by supp...
- PubMed ID: 10.5021/ad.2015.27.2.121, Retinoic Acid Promotes Interleukin-4 Plasmid-Dimethylsulfoxide Topical Transderm...
- PubMed ID: 10.3892/ijmm.2018.3547, CFTR ameliorates high glucose-induced oxidative stress and inflammation by media...
- PubMed ID: 10.3390/nu12030655, Modulation of Adhesion Process, E-Selectin and VEGF Production by Anthocyanins a...
- PubMed ID: 10.3390/molecules190812827, Anti-Inflammatory Effect of the Blueberry Anthocyanins Malvidin-3-Glucoside and ...
- PubMed ID: 10.3390/jcm10225449, Sophocarpine Alleviates Injury-Induced Intima Hyperplasia of Carotid Arteries by...
- PubMed ID: 10.3390/ijms18040844, Hypaphorine Attenuates Lipopolysaccharide-Induced Endothelial Inflammation via R...
- PubMed ID: 10.3177/jnsv.56.87, Protective Effects of Grape Seed Proanthocyanidin Extracts on Cerebral Cortex of...
- PubMed ID: 10.15537/smj.2021.42.6.20200753, Vascular cell adhesion molecule-1 in rheumatoid arthritis patients: Relation to ...
- PubMed ID: 10.1371/journal.pone.0178253, CTRP3 is a novel biomarker for diabetic retinopathy and inhibits HGHL-induced VC...
- PubMed ID: 10.1371/journal.pone.0158038, Protective Effect of Irisin on Atherosclerosis via Suppressing Oxidized Low Dens...
- PubMed ID: 10.1371/journal.pone.0140222, FGF-23/Vitamin D Axis in Type 1 Diabetes: The Potential Role of Mineral Metaboli...
- PubMed ID: 10.1248/bpb.33.752, Ferulic Acid Attenuates Adhesion Molecule Expression in Gamma-Radiated Human Umb...
- PubMed ID: 10.1177/1934578X1801300115, Malvidin and its Glycosides from Vaccinium ashei Improve Endothelial Function by...
- PubMed ID: 10.1159/000448141, Accumulation of Advanced Glycation End Products Involved in Inflammation and Con...
- PubMed ID: 10.1159/000358235, The Neurovascular Protective Effects of Huperzine A on D-Galactose-Induced Infla...
- PubMed ID: 10.1155/2018/3846029, Protective Role of Antioxidant Huskless Barley Extracts on TNF-α-Induced Endoth...
- PubMed ID: 10.1155/2017/9542702, Paracrine Potential of the Human Adipose Tissue-Derived Stem Cells to Modulate B...
- PubMed ID: 10.1155/2017/4391920, Uric Acid Induces Endothelial Dysfunction by Activating the HMGB1/RAGE Signaling...
- PubMed ID: 10.1152/ajpendo.00208.2011, Globular adiponectin counteracts VCAM-1-mediated monocyte adhesion via AdipoR1/N...
- PubMed ID: 10.1139/bcb-2018-0041, The combination of indirubin and isatin attenuates dextran sodium sulfate induce...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page