Anti-5-HT-6 HTR6 Antibody

Product Name

Anti-5-HT-6 HTR6 Antibody

View all 5-HT6 Antibodies

SKU/Catalog Number

A11122

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-5-HT-6 HTR6 Antibody (Catalog # A11122). Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-5-HT-6 HTR6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11122)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human 5-HT-6.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A11122 is reactive to HTR6 in Human

Applications

A11122 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

46.954kDa

Background of 5-HT6

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs.

Kohen R., J. Neurochem. 66:47-56(1996).
Kopatz S.A., Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
Gregory S.G., Nature 441:315-321(2006).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Validation Images & Assay Conditions

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Western blot analysis of extracts from A549 cells, using 5-HT-6 antibody A11122.

Gene/Protein Information For HTR6 (Source: Uniprot.org, NCBI)

Alternative Names

5-HT6; 5-hydroxytryptamine (serotonin) receptor 6,5-HT65-HT6R; HTR6; Serotonin receptor 6,5-HT-6,5-hydroxytryptamine receptor 6 HTR6 5-HT6, 5-HT6R 5-hydroxytryptamine receptor 6 5-hydroxytryptamine receptor 6|5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled|serotonin receptor 6

For more info on HTR6, check out the HTR6 Infographic

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In this infographic, you will see the following information for HTR6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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