Anti-Apoptosis regulator BAX Bax Antibody

Boster Bio Anti-Apoptosis regulator BAX Bax Antibody catalog # PA1013-1. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 128 publication(s).

Product Info Summary

SKU: PA1013-1
Size: 100μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: Flow Cytometry, WB

Product Name

Anti-Apoptosis regulator BAX Bax Antibody

See all BAX products

SKU/Catalog Number

PA1013-1

Size

100μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Apoptosis regulator BAX Bax Antibody catalog # PA1013-1. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Apoptosis regulator BAX Bax Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1013-1)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Bax (19-33aa IMKTGALLLQGFIQD), different from the related mouse and rat sequences by one amino acid.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross Reactivity

No cross reactivity with other proteins

Reactive Species

PA1013-1 is reactive to BAX in Human, Mouse, Rat

Applications

PA1013-1 is guaranteed for Flow Cytometry, WB Boster Guarantee

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive your next antibody/ELISA kit free of charge! Applicable to all scientists world wide.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse
Flow Cytometry, 1-3μg/1x106 cells, Human

Validation Images & Assay Conditions

Gene/Protein Information For BAX (Source: Uniprot.Org, NCBI)

Uniprot ID

Q07812

Gene ID

581

Gene Name

BAX

Full Name

Apoptosis regulator BAX

Weight

21.184kDa

Superfamily

Bcl-2 family

Alternative Names

apoptosis regulator BAX; Bax; BCL2-associated X protein; Bcl2-L-4; BCL2L4bcl2-L-4; Bcl-2-like protein 4 BAX BCL2L4 BCL2 associated X, apoptosis regulator apoptosis regulator BAX|BCL2 associated X protein|BCL2-associated X protein omega|Baxdelta2G9|Baxdelta2G9omega|Baxdelta2omega|bcl-2-like protein 4|bcl2-L-4

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on BAX, check out the BAX Infographic

BAX infographic

We have 30,000+ of these available, one for each gene! check them out.

In this infographic you will see the following information for BAX: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

PA1013-1 has been cited in 128 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Meng K,Yuan G,Bao H,Wang L,Ma R,Yu B,Zhao S.Interaction of HCCR-1 and Bax in breast cancer.J BUON.2019 May-Jun;24(3):1027-1037.PMID:31424657.
Species: Human
PA1013-1 usage in article: APP:WB, SAMPLE:MCF-7 CELL, DILUTION:NA

Su-Su Tang,Yi Ren,Xiao-Qian Ren,Jing-Ran Cao,Hao Hong,Hui Ji,Qing-Hua Hu,ERα and/or ERβ activation ameliorates cognitive impairment, neurogenesis and apoptosis in type 2 diabetes mellitus mice,Experimental Neurology,Volume 311,2019,Pages 33-43,ISSN 0014-4886,https://doi.org/10.1016/j.expneurol.2018.09.002.
Species: Mouse
PA1013-1 usage in article: APP:WB, SAMPLE:HIPPOCAMPUS TISSUE, DILUTION:1:500

Ren Q,Hu Z,Jiang Y,Tan X,Botchway BOA,Amin N,Lin G,Geng Y,Fang M.SIRT1 Protects Against Apoptosis by Promoting Autophagy in the Oxygen Glucose Deprivation/Reperfusion-Induced Injury.Front Neurol.2019 Dec 5;10:1289.doi:10.3389/fneur.2019.01289.PMID:31920915;PMCID:PMC6915092.
Species: Mouse
PA1013-1 usage in article: APP:WB, SAMPLE: PC12 CELL, DILUTION:1:400

Zhang X,Guo S,Huang X,Li B,Dai H,Wang C.A novel macrolide derivative ameliorates smoke-induced inflammation and emphysema by inhibiting NF-κB activation.Am J Transl Res.2021 Mar 15;13(3):1209-1220.PMID:33841650;PMCID:PMC8014339.
Species: Mouse
PA1013-1 usage in article: APP:IHC, SAMPLE:TRACHEAL TISSUE, DILUTION:1:50

Song P, Yan B, Lei F, Qiu Z, Zhang C, Wu Y, Chen S, Yang X, Shen D, Ma P. Continuous artificial light at night exacerbates diisononyl phthalate-induced learning and memory impairment in mice: Toxicological evidence. Food Chem Toxicol. 2021 Mar 9;151: 112102. doi: 10.1016/j.fct.2021.112102. Epub ahead of print. PMID: 33711377.
Species: Mouse
PA1013-1 usage in article: APP:IHC, SAMPLE: HIPPOCAMPUL TISSUE, DILUTION:NA

Junyi Tang,Kehua Fang,Chang Li,Xiaotian Chang,"ARHGEF10L Promotes Cervical Tumorigenesis via RhoA-Mediated Signaling",Evidence-Based Complementary and Alternative Medicine,vol.2021,Article ID 6683264,11 pages,2021.https://doi.org/10.1155/2021/6683264
Species: Human
PA1013-1 usage in article: APP:WB, SAMPLE:HELA CELL, DILUTION:NA

Zhang Z, Liu W, Shen M, Ma X, Li R, Jin X, Bai H, Gao L. Protective Effect of GM1 Attenuates Hippocampus and Cortex Apoptosis After Ketamine Exposure in Neonatal Rat via PI3K/AKT/GSK3β Pathway. Mol Neurobiol. 2021 Mar 17. doi: 10.1007/s12035-021-02346-5.Epub ahead of print.PMID: 33733293.
Species: Rat
PA1013-1 usage in article: APP:IHC, SAMPLE:TUMOR TISSUE, DILUTION:NA

Liang,T.,Wei,C.,Lu,S.,Qin,M.,Qin,G.,Zhang,Y. ... Yang,Y. (2021).Ginaton injection alleviates cisplatin‑induced renal interstitial fibrosis in rats via inhibition of apoptosis through regulation of the p38MAPK/TGF‑β1 and p38MAPK/HIF‑1α pathways.Biomedical
Species: Rat
PA1013-1 usage in article: APP:WB, SAMPLE:KIDNEY TISSUE, DILUTION:1:200

Xu Y,Chen W,Chen Z,Huang M,Yang F,Zhang Y.Mechanism of Action of Xiaoyao San in Treatment of Ischemic Stroke is Related to Anti-Apoptosis and Activation of PI3K/Akt Pathway.Drug Des Devel Ther.2021 Feb 22;15:753-767.doi:10.2147/DDDT.S280217.PMID:33654381;
Species: Rat
PA1013-1 usage in article: APP:WB, SAMPLE:PC12 CELL, DILUTION:1:500

Zhou L,Liu Y,Wang Z,Liu D,Xie B,Zhang Y,Yuan M,Tse G,Li G,Xu G,Liu T.Activation of NADPH oxidase mediates mitochondrial oxidative stress and atrial remodeling in diabetic rabbits.Life Sci.2021 Feb 15:119240.doi:10.1016/j.lfs.2021.119240.Epub ahead of prin
Species: Rabbit
PA1013-1 usage in article: APP:WB, SAMPLE:ATRIAL TISSUE, DILUTION:1:300

Yan Zhang,Linchao Zhang,JiaLu Bao et al.Perfluorooctanoic Acid Exposure in Early Pregnancy Induces Oxidative Stress in The Uterus and Liver in Mice,13 February 2021,PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-160447
Species: Mouse
PA1013-1 usage in article: APP:IHC, SAMPLE:UTREUS, DILUTION:NA

Li C,Liu W,Li X,Zhang Z,Qi H,Liu S,Yan N,Xing Y,Hölscher C,Wang Z.The novel GLP-1/GIP analogue DA5-CH reduces tau phosphorylation and normalizes theta rhythm in the icv. STZ rat model of AD.Brain Behav.2020 Mar;10(3):e01505.doi:10.1002/brb3.1505.Epub 2020
Species: Mouse,Rat
PA1013-1 usage in article: APP:WB, SAMPLE:HIPPOCAMPUS TISSUE, DILUTION:1:2500

Zhu N,Ruan J,Yang X,Huang Y,Jiang Y,Wang Y,Cai D,Geng Y,Fang M.Triptolide improves spinal cord injury by promoting autophagy and inhibiting apoptosis.Cell Biol Int.2020 Mar;44(3):785-794.doi:10.1002/cbin.11273.Epub 2019 Dec 9.PMID:31774600.
Species: Mouse
PA1013-1 usage in article: APP:WB, SAMPLE:SPINAL CORD TISSUE, DILUTION:1:400

Zhang Q,Duan HX,Li RL,Sun JY,Liu J,Peng W,Wu CJ,Gao YX. Inducing Apoptosis and Suppressing Inflammatory Reactions in Synovial Fibroblasts are Two Important Ways for Guizhi-Shaoyao-Zhimu Decoction Against Rheumatoid Arthritis. J Inflamm Res.2021 Jan 26;14:
Species: Human
PA1013-1 usage in article: APP:WB, SAMPLE:MH7A CELL, DILUTION:1:300

Lu Kong,Yongya Wu,Wangcheng Hu,Lin Liu,Yuying Xue,Geyu Liang,Mechanisms underlying reproductive toxicity induced by nickel nanoparticles identified by comprehensive gene expression analysis in GC-1 spg cells,Environmental Pollution,2021,116556,ISSN 0269-7
Species: Mouse
PA1013-1 usage in article: APP:WB, SAMPLE:GC-1 CELL, DILUTION:1:1000

Liu L,Liu F,Sun Z,Peng Z,You T,Yu Z. LncRNA NEAT1 promotes apoptosis and inflammation in LPS-induced sepsis models by targeting miR-590-3p. Exp Ther Med.2020 Oct; 20(4):3290-3300. doi:10.3892/etm.2020.9079. Epub 2020 Jul 29.PMID:32855700;PMCID:PMC7444425.
Species: Human
PA1013-1 usage in article: APP:WB, SAMPLE:H9C2 CELL, DILUTION:1:1000

Chai BY,Gong FK,Chen ZH,Li ZX,Zhang B.System Prediction and Validation of TCM for Chronic Myeloid Leukemia Treatment from the Perspective of Low-Toxicity Chemotherapy: A Stilbene α-Viniferin Has a Proapoptotic Effect on K562 Cells via the Mitochondrial Pa
Species: Human
PA1013-1 usage in article: APP:WB, SAMPLE:K562 CELL, DILUTION:1:400

Zhao Y,Tang N,Xi D,Huang Z,Zhang T,Liu Y,Wang L,Tang Y,Zhong H,He F.Calcilytic NPS2143 promotes proliferation and inhibits apoptosis of spontaneously hypertensive rat vascular smooth muscle cells via activation of the renin-angiotensin system.Exp Ther Med
Species: Rat
PA1013-1 usage in article: APP:WB, SAMPLE:VSMCS, DILUTION:1:200

Wei JL,Wu CJ,Chen JJ,Shang FT,Guo SG,Zhang XC,Liu H.LncRNA NEAT1 promotes the progression of sepsis-induced myocardial cell injury by sponging miR-144-3p.Eur Rev Med Pharmacol Sci.2020 Jan;24(2):851-861.doi:10.26355/eurrev_202001_20069.PMID:32016991.
Species: Mouse
PA1013-1 usage in article: APP:WB, SAMPLE:HL-1 CELLS, DILUTION:1:1000

Cao H,Lin W,Xie C,Yao L.P53 Plays an Important Role in the Early Stage of Autologous Heterotopic Transplantation of Ovaries into the Backs of Mice. Transplant Proc. 2020 Jan-Feb;52(1):406-413.doi: 10.1016/j.transproceed.2019.11.028.Epub 2020 Jan 3.PMID:31
Species: Mouse
PA1013-1 usage in article: APP:WB, SAMPLE:OVARIAN TISSUE, DILUTION:1:400

Zhu X,Yao Y,Yang J,Zhengxie J,Li X,Hu S,Zhang A,Dong J,Zhang C,Gan G.COX-2-PGE2 signaling pathway contributes to hippocampal neuronal injury and cognitive impairment in PTZ-kindled epilepsy mice. Int Immunopharmacol. 2020 Oct;87:106801.doi: 10.1016/j.inti
Species: Mouse
PA1013-1 usage in article: APP:WB, SAMPLE:HIPPOCAMPUL TISSUE, DILUTION:1:2000

Yue W,Cunlin G,Lu H,Yuanqing Z,Yanjun T,Qiong W. Neuroprotective effect of intermittent hypobaric hypoxia preconditioning on cerebral ischemia/reperfusion in rats. Int J Clin Exp Pathol.2020 Nov 1;13(11):2860-2869.PMID:33284899;PMCID:PMC7716138.
Species: Rat
PA1013-1 usage in article: APP:WB, SAMPLE:NEURONS, DILUTION:1:1500

Wang P,Wang C,Liu C. Antitumor effects of dioscin in A431 cells via adjusting ATM/p53-mediated cell apoptosis, DNA damage and migration. Oncol Lett. 2021 Jan;21(1):59.doi:10.3892/ol.2020.12321.Epub 2020 Nov 19.PMID:33281970;PMCID:PMC7709553.
Species: Human
PA1013-1 usage in article: APP:WB, SAMPLE:A431 CELLS, DILUTION:NA

Triptolide inhibits proliferation, differentiation and induces apoptosis of osteoblastic MC3T3-E1 cells

Fibroblast growth factor 21 protects rat cardiomyocytes from endoplasmic reticulum stress by promoting the fibroblast growth factor receptor 1-extracellular signal-regulated kinase 1/2 signaling pathway

Ailanthone induces G2/M cell cycle arrest and apoptosis of SGC-7901 human gastric cancer cells

Hepatitis E Virus Induces Hepatocyte Apoptosis via Mitochondrial Pathway in Mongolian Gerbils

Magnesium isoglycyrrhizinate ameliorates doxorubicin-induced acute cardiac and hepatic toxicity via anti-oxidant and anti-apoptotic mechanisms in mice

Ouabain targets the Na+/K+-ATPase ?3 isoform to inhibit cancer cell proliferation and induce apoptosis

Downregulation of BRAF-activated non-coding RNA suppresses the proliferation, migration and invasion, and induces apoptosis of hepatocellular carcinoma cells

Blockade of sonic hedgehog signaling decreases viability and induces apoptosis in retinoblastoma cells: The key role of the PI3K/Akt pathway

Emodin alleviates severe acute pancreatitis-associated acute lung injury by decreasing pre-B-cell colony-enhancing factor expression and promoting polymorphonuclear neutrophil apoptosis

Siva 1 inhibits proliferation, migration and invasion by phosphorylating Stathmin in ovarian cancer cells

RKTG overexpression inhibits proliferation and induces apoptosis of human leukemia cells via suppression of the ERK and PI3K/AKT signaling pathways

Nogo receptor knockdown and ciliary neurotrophic factor attenuate diabetic retinopathy in streptozotocin-induced diabetic rats

BMP-7 suppresses excessive scar formation by activating the BMP-7/Smad1/5/8 signaling pathway

Effects of Bushen Tianjing Recipe in a rat model of tripterygium glycoside-induced premature ovarian failure

Cardioprotective effects of traditional Chinese medicine Guanmaitong on acute myocardial infarction

Vanadium toxicity in the thymic development

Ibutilide protects against cardiomyocytes injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways

The Effects of Fasudil at Different Doses on Acute Myocardial Infarction in Rats

Effect of curcumin on Bcl-2 and Bax expression in nude mice prostate cancer.

Adipose-Derived Mesenchymal Stem Cells Transplantation Alleviates Renal Injury in Streptozotocin-Induced Diabetic Nephropathy

A preliminary study of the effect of ECRG4 overexpression on the proliferation and apoptosis of human laryngeal cancer cells and the underlying mechanisms

In vitro and in vivo antitumor effects of acetylshikonin isolated from Arnebia euchroma (Royle) Johnst (Ruanzicao) cell suspension cultures

Effects of garlicin on apoptosis in rat model of colitis

Croton Tiglium Extract Induces Apoptosis via Bax/Bcl-2 Pathways in Human Lung Cancer A549 Cells

Knockdown of High Mobility Group-Box 3 (HMGB3) Expression Inhibits Proliferation, Reduces Migration, and Affects Chemosensitivity in Gastric Cancer Cells

Valproate Attenuates Nitroglycerin-Induced Trigeminovascular Activation by Preserving Mitochondrial Function in a Rat Model of Migraine

A novel polysaccharide from Sargassum integerrimum induces apoptosis in A549 cells and prevents angiogensis in vitro and in vivo

Catalpol inhibits apoptosis in hydrogen peroxide-induced cardiac myocytes through a mitochondrial-dependent caspase pathway

Radix Ilicis Pubescentis total flavonoids combined with mobilization of bone marrow stem cells to protect against cerebral ischemia/reperfusion injury

Glycyrrhizic Acid Attenuates Sepsis-Induced Acute Kidney Injury by Inhibiting NF-?B Signaling Pathway

Mesenchymal stem cells promote colorectal cancer progression through AMPK/mTOR-mediated NF-?B activation

Fenofibrate, a PPAR? agonist, protect proximal tubular cells from albumin-bound fatty acids induced apoptosis via the activation of NF-kB

Glycyrrhizic Acid Prevents Sepsis-Induced Acute Lung Injury and Mortality in Rats

Effect of ligustilide on Ang II-induced hypertrophy in cardiomyocytes and the potential mechanisms

Wang Y, Li Y, Yang W, Gao S, Lin J, Wang T, Zhou K, Hu H. Am J Transl Res. 2018 Mar 15;10(3):796-805. eCollection 2018. Ginsenoside Rb1 inhibit apoptosis in rat model of Alzheimer’s disease induced by Aβ1-40

Qi QM, Xue YC, Lv J, Sun D, Du JX, Cai SQ, Li YH, Gu TC, Wang MB. Oncol Lett. 2018 May;15(5):6400-6408. doi: 10.3892/ol.2018.8177. Epub 2018 Mar 5. Ginkgolic acids induce HepG2 cell death via a combination of apoptosis, autophagy and the mitochond...

Chang L, Guo F, Lv Y, Wang Y, Huo B, Wang L, Liu W. Mol Biol Rep. 2013 Jan;40(1):669-73. Doi: 10.1007/S11033-012-2106-X. Epub 2012 Oct 11. The Inhibitory Effects Of Endostar Combined With Chemotherapy On Human Esophageal Squamous Cell Carcinoma Xe...

Zhao X, Chen Q, Li Y, Tang H, Liu W, Yang X. Eur J Pharm Biopharm. 2015 Jun;93:27-36. Doi: 10.1016/J.Ejpb.2015.03.003. Epub 2015 Mar 11. Doxorubicin And Curcumin Co-Delivery By Lipid Nanoparticles For Enhanced Treatment Of Diethylnitrosamine-Induc...

Lin S, Lin K, Li W, Zhou X, Huang T. Endocrine. 2010 Jun;37(3):460-6. Doi: 10.1007/S12020-010-9337-1. Epub 2010 Apr 21. Maternal Diabetes Increases Apoptosis In Mice Oocytes, Not 2-Cell Embryos.

Yan X, Wu L, Li B, Meng X, Dai H, Zheng Y, Fu J. Cardiovasc Toxicol. 2015 Jul 3. [Epub Ahead Of Print] Cyanidin-3-O-Glucoside Induces Apoptosis And Inhibits Migration Of Tumor Necrosis Factor-??-Treated Rat Aortic Smooth Muscle Cells.

Du F, Ding Y, Zou J, Li Z, Tian J, She R, Wang D, Wang H, Lv D, Chang L. Plos One. 2015 May 22;10(5):E0127047. Doi: 10.1371/Journal.Pone.0127047. Ecollection 2015. Morphology And Molecular Mechanisms Of Hepatic Injury In Rats Under Simulated Weigh...

Bu Tl, Jia Yd, Lin Jx, Mi Yl, Zhang Cq. J Zhejiang Univ Sci B. 2012 Apr;13(4):318-26. Doi: 10.1631/Jzus.B1100318. Alleviative Effect Of Quercetin On Germ Cells Intoxicated By 3-Methyl-4-Nitrophenol From Diesel Exhaust Particles.

Li Tt, Zhang Jf, Fei Sj, Zhu Sp, Zhu Jz, Qiao X, Liu Zb. Acta Pharmacol Sin. 2014 Feb;35(2):185-94. Doi: 10.1038/Aps.2013.140. Epub 2013 Dec 23. Glutamate Microinjection Into The Hypothalamic Paraventricular Nucleus Attenuates Ulcerative Colitis I...

Wang Y, Wang S, Cui W, He J, Wang Z, Yang X. Neural Regen Res. 2013 Aug 5;8(22):2021-9. Doi: 10.3969/J.Issn.1673-5374.2013.22.001. Olive Leaf Extract Inhibits Lead Poisoning-Induced Brain Injury.

Wei Q, He W, Lu Y, Yao J, Cao X. Oncol Lett. 2012 Sep;4(3):438-442. Epub 2012 Jun 7. Effect Of The Tumor Suppressor Gene Ing4 On The Proliferation Of Mcf-7 Human Breast Cancer Cells.

Zhou Yx, Qiu Yq, Xu Lq, Guo J, Li Lj. Afr J Tradit Complement Altern Med. 2012 Apr 2;9(3):405-11. Ecollection 2012. Xiao-Chai-Hu Tang In Treating Model Mice With D-Galactosamine-Induced Liver Injury.

Song Y, Zhang G, Zhu X, Pang Z, Xing F, Quan S. Oncol Lett. 2012 Sep;4(3):419-422. Epub 2012 Jun 19. Overexpression Of The Hydatidiform Mole-Related Gene F10 Inhibits Apoptosis In A549 Cells Through Downregulation Of Bcl2-Associated X Protein And ...

Sun Y, Xu Hj, Zhao Yx, Wang Lz, Sun Lr, Wang Z, Sun Xf. Evid Based Complement Alternat Med. 2013;2013:690164. Doi: 10.1155/2013/690164. Epub 2013 Mar 19. Crocin Exhibits Antitumor Effects On Human Leukemia Hl-60 Cells In Vitro And In Vivo.

Shuai H, Zhang J, Zhang J, Xie J, Zhang M, Yu Y, Zhang L. Endocr Res. 2011;36(1):25-34. Doi: 10.3109/07435800.2010.534753. Erythropoietin Protects Pancreatic ??-Cell Line Nit-1 Cells Against Cytokine-Induced Apoptosis Via Phosphatidylinositol 3-Ki...

Chen J, Huang Rb. Neurosciences (Riyadh). 2009 Oct;14(4):343-8. Protective Effect Of Yulangsan Polysaccharide On Focal Cerebral Ischemia/Reperfusion Injury In Rats And Its Underlying Mechanism.

Liu W, Zheng Q, Wang Y, Han X, Yuan L, Zhao M. Neurochem Res. 2015 Jan;40(1):70-80. Doi: 10.1007/S11064-014-1467-Z. Epub 2014 Nov 5. Transplantation Of Olfactory Ensheathing Cells Attenuates Acute Carbon Monoxide Poisoning-Induced Brain Damages In...

Yuan F, Dong P, Wang X, Fu X, Dai M, Zhang W. Exp Toxicol Pathol. 2013 Nov;65(7-8):1011-8. Doi: 10.1016/J.Etp.2013.02.004. Epub 2013 Mar 19. Toxicological Effects Of Cigarette Smoke On Ana-1 Macrophages In Vitro.

Luo Q, Li Z, Yan J, Zhu F, Xu Rj, Cai Yz. J Med Food. 2009 Aug;12(4):695-703. Doi: 10.1089/Jmf.2008.1232. Lycium Barbarum Polysaccharides Induce Apoptosis In Human Prostate Cancer Cells And Inhibits Prostate Cancer Growth In A Xenograft Mouse Mode...

Wu Cy, Tang Zh, Jiang L, Li Xf, Jiang Zs, Liu Ls. Mol Cell Biochem. 2012 Jan;359(1-2):347-58. Doi: 10.1007/S11010-011-1028-6. Epub 2011 Aug 17. Pcsk9 Sirna Inhibits Huvec Apoptosis Induced By Ox-Ldl Via Bcl/Bax-Caspase9-Caspase3 Pathway.

Rasul A, Yu B, Zhong L, Khan M, Yang H, Ma T. Oncol Rep. 2012 May;27(5):1481-7. Doi: 10.3892/Or.2012.1694. Epub 2012 Feb 21. Cytotoxic Effect Of Evodiamine In Sgc-7901 Human Gastric Adenocarcinoma Cells Via Simultaneous Induction Of Ap...

Li Y, Gu Wj, Liu Hl. Dig Dis Sci. 2012 Aug;57(8):2072-8. Doi: 10.1007/S10620-012-2132-5. Epub 2012 May 10. Induction Of Pancreatic Cancer Cell Apoptosis And Enhancement Of Gemcitabine Sensitivity By Rap80 Sirna.

Wang Y, Liu X, Zhang D, Chen J, Liu S, Berk M. Bmc Med. 2013 Feb 8;11:32. Doi: 10.1186/1741-7015-11-32. The Effects Of Apoptosis Vulnerability Markers On The Myocardium In Depression After Myocardial Infarction.

Gu Wj, Liu Hl. Anticancer Drugs. 2013 Jul;24(6):566-76. Doi: 10.1097/Cad.0B013E3283608Bc5. Induction Of Pancreatic Cancer Cell Apoptosis, Invasion, Migration, And Enhancement Of Chemotherapy Sensitivity Of Gemcitabine, 5-Fu, And Oxaliplatin By Hnr...

Wu K, Liu Y, Lv Y, Cui L, Li W, Chen J, Liang Nc, Li L. Oncol Rep. 2013 Jun;29(6):2101-8. Doi: 10.3892/Or.2013.2375. Epub 2013 Apr 3. Ent-11??-Hydroxy-15-Oxo-Kaur-16-En-19-Oic-Acid Induces Apoptosis And Cell Cycle Arrest In Cne-2Z Nasopharyngeal C...

Qin R, Shen H, Cao Y, Fang Y, Li H, Chen Q, Xu W. Plos One. 2013 Oct 1;8(10):E76486. Doi: 10.1371/Journal.Pone.0076486. Ecollection 2013. Tetrandrine Induces Mitochondria-Mediated Apoptosis In Human Gastric Cancer Bgc-823 Cells.

Wei T, Tian W, Liu F, Xie G. Biochem Biophys Res Commun. 2014 May 16;447(4):666-71. Doi: 10.1016/J.Bbrc.2014.04.074. Epub 2014 Apr 19. Protective Effects Of Exogenous ??-Hydroxybutyrate On Paraquat Toxicity In Rat Kidney.

Wang Y, Zhang H, Chai F, Liu X, Berk M,,,,. Bmc Psychiatry. 2014 Dec 4;14:349. Doi: 10.1186/S12888-014-0349-X. The Effects Of Escitalopram On Myocardial Apoptosis And The Expression Of Bax And Bcl-2 During Myocardial Ischemia/Reperfusion In A Mode...

Wu C, Dong S, Li Y. Int J Mol Med. 2015 Apr;35(4):893-900. Doi: 10.3892/Ijmm.2015.2105. Epub 2015 Feb 18. Effects Of Mirna-455 On Cardiac Hypertrophy Induced By Pressure Overload.

Han N, Yu L, Song Z, Luo L, Wu Y. Mol Med Rep. 2015 Jul;12(1):1098-106. Doi: 10.3892/Mmr.2015.3540. Epub 2015 Mar 24. Agmatine Protects M??ller Cells From High-Concentration Glucose-Induced Cell Damage Via N-Methyl-D-Aspartic Acid Receptor Inhibit...

Sun J, Zhang H, Guan L, Zhou H, Sun M. Int J Clin Exp Med. 2015 Jan 15;8(1):358-67. Ecollection 2015. Alpha-Lipoic Acid Attenuates Trinitrobenzene Sulfonic Acid-Induced Ulcerative Colitis In Mice.

Rasul A, Ding C, Li X, Khan M, Yi F, Ali M, Ma T. Apoptosis. 2012 Oct;17(10):1104-19. Doi: 10.1007/S10495-012-0742-1. Dracorhodin Perchlorate Inhibits Pi3K/Akt And Nf-??b Activation, Up-Regulates The Expression Of P53, And Enhances Apoptosis.

Yin W, Li B, Li X, Yu F, Cai Q, Zhang Z, Wang J, Zhang J, Zhou R, Cheng M, Gao H. J Cardiovasc Pharmacol. 2015 Jan;65(1):13-21. Doi: 10.1097/Fjc.0000000000000157. Critical Role Of Prohibitin In Endothelial Cell Apoptosis Caused By Glycated Low-Den...

Zhou Y, Tan X, Kuang W, Liu L, Wan L. Transl Res. 2012 Jun;159(6):464-72. Doi: 10.1016/J.Trsl.2011.09.007. Epub 2011 Oct 24. Erythromycin Ameliorates Cigarette-Smoke-Induced Emphysema And Inflammation In Rats.

Tang Y, Zhang X, Qi F, Chen M, Li Y, Liu L, He W, Li Z, Zu X. Exp Ther Med. 2015 May;9(5):1851-1856. Epub 2015 Feb 25. Afatinib Inhibits Proliferation And Invasion And Promotes Apoptosis Of The T24 Bladder Cancer Cell Line.

Ban Jb, Fan Xw, Huang Q, Li Bf, Chen C, Zhang Hc, Xu Sq. Plos One. 2014 May 16;9(5):E97607. Doi: 10.1371/Journal.Pone.0097607. Ecollection 2014. Mono-(2-Ethylhexyl) Phthalate Induces Injury In Human Umbilical Vein Endothelial Cells.

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17 Customer Q&As for Anti-Apoptosis regulator BAX Bax Antibody

Question

Is a blocking peptide available for product anti-Bax antibody (PA1013-1)?

Verified Customer

Verified customer

Asked: 2020-04-23

Answer

We do provide the blocking peptide for product anti-Bax antibody (PA1013-1). If you would like to place an order for it please contact [email protected] and make a special request.

Boster Scientific Support

Answered: 2020-04-23

Question

Is this PA1013-1 anti-Bax antibody reactive to the isotypes of BAX?

Verified Customer

Verified customer

Asked: 2020-04-13

Answer

The immunogen of PA1013-1 anti-Bax antibody is A synthetic peptide corresponding to a sequence at the N-terminus of human Bax(19-33aa IMKTGALLLQGFIQD), different from the related mouse and rat sequences by one amino acid. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?

Boster Scientific Support

Answered: 2020-04-13

Question

Will PA1013-1 anti-Bax antibody work on parafin embedded sections? If so, which fixation method do you recommend we use (PFA, paraformaldehyde, other)?

Verified Customer

Verified customer

Asked: 2020-02-28

Answer

It shows on the product datasheet, PA1013-1 anti-Bax antibody as been validated on WB. It is best to use PFA for fixation because it has better tissue penetration ability. PFA needs to be prepared fresh before use. Long term stored PFA turns into formalin, as the PFA molecules congregate and become formalin.

Boster Scientific Support

Answered: 2020-02-28

Question

I am interested in using your anti-Bax antibody for post-embryonic camera-type eye morphogenesis studies. Has this antibody been tested with western blotting on tissue lysate? We would like to see some validation images before ordering.

Verified Customer

Verified customer

Asked: 2019-10-10

Answer

We appreciate your inquiry. This PA1013-1 anti-Bax antibody is validated on rat ovary tissue, testis tissue, tissue lysate, kidney tissue, brain tissue, hela cell lysate, mm231 cell lysate, a549 cell lysate, jurkat cell lysate, human placenta tissue, a431 cells. It is guaranteed to work for Flow Cytometry, WB in human, mouse, rat. Our Boster guarantee will cover your intended experiment even if the sample type has not been be directly tested.

Boster Scientific Support

Answered: 2019-10-10

Question

Thank you for helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for mucosa of transverse colon using anti-Bax antibody PA1013-1. Let me know if you need anything else.

Verified Customer

Verified customer

Asked: 2019-09-16

Answer

We appreciate the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2019-09-16

Question

Can you help my question with product PA1013-1, anti-Bax antibody. I was wondering if it would be possible to conjugate this antibody with biotin. I would need it to be without BSA or sodium azide. I am planning on using a buffer exchange of sodium azide with PBS only. Would there be problems for me to conjugate the antibody and store it in -20 degrees in small aliquots?

Verified Customer

Verified customer

Asked: 2019-08-19

Answer

We do not advise storing this antibody with PBS buffer only in -20 degrees. If you want to store it in -20 degrees it is best to add some cryoprotectant like glycerol. If you want carrier free PA1013-1 anti-Bax antibody, we can provide it to you in a special formula with trehalose and/or glycerol. These molecules will not interfere with conjugation chemistry and provide a good level of protection for the antibody from degradation. Please be sure to specify this in your purchase order.

Boster Scientific Support

Answered: 2019-08-19

Question

Does anti-Bax antibody PA1013-1 work on monkey WB with brain?

Verified Customer

Verified customer

Asked: 2019-07-19

Answer

Our lab technicians have not tested anti-Bax antibody PA1013-1 on monkey. You can run a BLAST between monkey and the immunogen sequence of anti-Bax antibody PA1013-1 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated monkey samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in monkey brain in WB, you can get your next antibody for free.

Boster Scientific Support

Answered: 2019-07-19

Question

Is there a BSA free version of anti-Bax antibody PA1013-1 available?

Verified Customer

Verified customer

Asked: 2019-06-14

Answer

We appreciate your recent telephone inquiry. I can confirm that some lots of this anti-Bax antibody PA1013-1 are BSA free. For now, these lots are available and we can make a BSA free formula for you free of charge. It will take 3 extra days to prepare. If you require this antibody BSA free again in future, please do not hesitate to contact me and I will be pleased to check which lots we have in stock that are BSA free.

Boster Scientific Support

Answered: 2019-06-14

Question

We are interested in to test anti-Bax antibody PA1013-1 on human mucosa of transverse colon for research purposes, then I may be interested in using anti-Bax antibody PA1013-1 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

Verified Customer

Verified customer

Asked: 2018-12-21

Answer

The products we sell, including anti-Bax antibody PA1013-1, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2018-12-21

Question

We bought anti-Bax antibody for Flow Cytometry on mucosa of transverse colon a few years ago. I am using human, and We intend to use the antibody for WB next. I was wanting to use examining mucosa of transverse colon as well as ovarian carcinoma in our next experiment. Do you have any suggestion on which antibody would work the best for WB?

P. Dhar

Verified customer

Asked: 2018-06-12

Answer

I looked at the website and datasheets of our anti-Bax antibody and it appears that PA1013-1 has been validated on human in both Flow Cytometry and WB. Thus PA1013-1 should work for your application. Our Boster satisfaction guarantee will cover this product for WB in human even if the specific tissue type has not been validated. We do have a comprehensive range of products for WB detection and you can check out our website bosterbio.com to find out more information about them.

Boster Scientific Support

Answered: 2018-06-12

Question

We have been able to see staining in mouse skin. Do you have any suggestions? Is anti-Bax antibody supposed to stain skin positively?

Verified Customer

Verified customer

Asked: 2018-03-22

Answer

From literature skin does express BAX. From Uniprot.org, BAX is expressed in mucosa of transverse colon, b-cell, brain, ovarian carcinoma, skin, among other tissues. Regarding which tissues have BAX expression, here are a few articles citing expression in various tissues:
B-cell, Pubmed ID: 8358790
Brain, Pubmed ID: 9920818
Ovarian carcinoma, Pubmed ID: 14702039
Skin, Pubmed ID: 15489334

Boster Scientific Support

Answered: 2018-03-22

Question

My colleagues were content with the WB result of your anti-Bax antibody. However we have seen positive staining in skin isoform beta: cytoplasm. using this antibody. Is that expected? Could you tell me where is BAX supposed to be expressed?

K. Johnson

Verified customer

Asked: 2017-11-21

Answer

According to literature, skin does express BAX. Generally BAX expresses in isoform alpha: mitochondrion outer membrane, isoform beta: cytoplasm., isoform gamma: cytoplasm., isoform delta: cytoplasm. Regarding which tissues have BAX expression, here are a few articles citing expression in various tissues:
B-cell, Pubmed ID: 8358790
Brain, Pubmed ID: 9920818
Ovarian carcinoma, Pubmed ID: 14702039
Skin, Pubmed ID: 15489334

Boster Scientific Support

Answered: 2017-11-21

Question

I have attached the WB image, lot number and protocol we used for mucosa of transverse colon using anti-Bax antibody PA1013-1. Please let me know if you require anything else.

Verified Customer

Verified customer

Asked: 2017-09-22

Answer

Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2017-09-22

Question

I was wanting to use your anti-Bax antibody for WB for human mucosa of transverse colon on frozen tissues, but I want to know if it has been validated for this particular application. Has this antibody been validated and is this antibody a good choice for human mucosa of transverse colon identification?

K. Kulkarni

Verified customer

Asked: 2017-02-16

Answer

You can see on the product datasheet, PA1013-1 anti-Bax antibody has been validated for Flow Cytometry, WB on human, mouse, rat tissues. We have an innovator award program that if you test this antibody and show it works in human mucosa of transverse colon in IHC-frozen, you can get your next antibody for free.

Boster Scientific Support

Answered: 2017-02-16

Question

I see that the anti-Bax antibody PA1013-1 works with WB, what is the protocol used to produce the result images on the product page?

A. Jackson

Verified customer

Asked: 2016-09-09

Answer

You can find protocols for WB on the "support/technical resources" section of our navigation menu. If you have any further questions, please send an email to [email protected]

Boster Scientific Support

Answered: 2016-09-09

Question

Does anti-Bax antibody PA1013-1 work for WB with mucosa of transverse colon?

G. Krishna

Verified customer

Asked: 2015-06-02

Answer

According to the expression profile of mucosa of transverse colon, BAX is highly expressed in mucosa of transverse colon. So, it is likely that anti-Bax antibody PA1013-1 will work for WB with mucosa of transverse colon.

Boster Scientific Support

Answered: 2015-06-02

Question

We are currently using anti-Bax antibody PA1013-1 for mouse tissue, and we are well pleased with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it true that the antibody can work on monkey tissues as well?

D. Carter

Verified customer

Asked: 2015-02-02

Answer

The anti-Bax antibody (PA1013-1) has not been validated for cross reactivity specifically with monkey tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in monkey you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2015-02-02

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PA1013-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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