Anti-Cytochrome P450 2C8/9/18/19 CYP2C18 Antibody

Product Name

Anti-Cytochrome P450 2C8/9/18/19 CYP2C18 Antibody

View all Cytochrome P450 2C18 Antibodies

SKU/Catalog Number

A07005

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-Cytochrome P450 2C8/9/18/19 CYP2C18 Antibody (Catalog # A07005). Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Cytochrome P450 2C8/9/18/19 CYP2C18 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07005)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human Cytochrome P450 2C8/9/18/19.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A07005 is reactive to CYP2C18 in Human

Applications

A07005 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

55.711kDa

Background of Cytochrome P450 2C18

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

Romkes M., Biochemistry 30:3247-3255(1991).
de Morais S.M., Biochem. Biophys. Res. Commun. 194:194-201(1993).
Deloukas P., Nature 429:375-381(2004).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Validation Images & Assay Conditions

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Western blot analysis of extracts from LOVO cells, using Cytochrome P450 2C8/9/18/19 antibody A07005.

Gene/Protein Information For CYP2C18 (Source: Uniprot.org, NCBI)

Alternative Names

(S)-mephenytoin hydroxylase associated cytochrome P450; CPCI; CYP2C; CYP2C17; CYPIIC18; cytochrome P450 2C18; cytochrome P450, family 2, subfamily C, polypeptide 18; cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 17; cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 18; Cytochrome P450-6b/29c; DKFZp686I24235; EC 1.14.14.1; flavoprotein-linked monooxygenase; microsomal monooxygenase; P450-6B/29C; P450IIC17; unspecific monooxygenase CYP2C18 CPCI, CYP2C, CYP2C17, P450-6B/29C, P450IIC17 cytochrome P450 family 2 subfamily C member 18 cytochrome P450 2C18|(S)-mephenytoin hydroxylase associated cytochrome P450|CYPIIC18|cytochrome P450, family 2, subfamily C, polypeptide 18|cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 17|cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 18|cytochrome P450-6B/29C|flavoprotein-linked monooxygenase|microsomal monooxygenase|unspecific monooxygenase

For more info on CYP2C18, check out the CYP2C18 Infographic

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In this infographic, you will see the following information for CYP2C18: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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