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Product Info Summary
| SKU: | A04085-2 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-GOT1 Antibody
SKU/Catalog Number
A04085-2
Size
100ul
Form
Liquid
Description
Boster Bio Anti-GOT1 Antibody catalog # A04085-2. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-GOT1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04085-2)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human GALR2
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A04085-2 is reactive to GOT1 in Human, Mouse, Rat
Applications
A04085-2 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
46.248kDa
Background of GOT1
Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor.
Lee J., Gene 138:247-251(1994).
Cance W.G., Cell Growth Differ. 5:1347-1355(1994).
Zhang Y., Mol. Cell. Proteomics 4:1240-1250(2005).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:200
ICC/IF: 1:10-1:100
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-GOT1 Antibody A04085-2
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For GOT1 (Source: Uniprot.org, NCBI)
Gene Name
GOT1
Full Name
Aspartate aminotransferase, cytoplasmic
Weight
46.248kDa
Superfamily
class-I pyridoxal-phosphate-dependent aminotransferase family
Alternative Names
aspartate aminotransferase, cytoplasmic; EC 2.6.1.1; GIG18; Glutamate oxaloacetate transaminase 1; glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1); growth-inhibiting protein 18; Transaminase A GOT1 AST1, ASTQTL1, GIG18, cAspAT, cCAT glutamic-oxaloacetic transaminase 1 aspartate aminotransferase, cytoplasmic|aspartate aminotransferase 1|aspartate transaminase 1|cysteine aminotransferase, cytoplasmic|cysteine transaminase, cytoplasmic|glutamate oxaloacetate transaminase 1|glutamic-oxaloacetic transaminase 1, soluble|growth-inhibiting protein 18|testis secretory sperm-binding protein Li 196a|transaminase A
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GOT1, check out the GOT1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GOT1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-GOT1 Antibody (A04085-2)
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No publications found for A04085-2
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Customer Reviews
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