Anti-Hepatocyte growth factor HGF Antibody

HGF antibody

Boster Bio Anti-Hepatocyte growth factor HGF Antibody catalog # A00089. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat. Cited in 6 publication(s).

Product Info Summary

SKU: A00089
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IHC, WB

Product Name

Anti-Hepatocyte growth factor HGF Antibody

View all HGF Antibodies

SKU/Catalog Number

A00089

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Hepatocyte growth factor HGF Antibody catalog # A00089. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Hepatocyte growth factor HGF Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00089)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human Rad51 around the phosphorylation site of Y315.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A00089 is reactive to HGF in Human, Mouse, Rat

Applications

A00089 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

83.134kDa

Background of HGF

Beta amyloid, often abbreviated as A-beta, is a protein that builds up in the brains of persons with Alzheimer's disease, collecting in clumps called plaques or senile plaques. While some researchers question whether beta amyloid is the cause of the dementia, most agree that it is involved in the disruption of thinking that is a hallmark of the disease. In some cases of familial Alzheimer's disease, mutations in genes for the proteins called the presenilins lead to increased production of amyloid. Researchers have been looking at how presenilin-1 in particular contributes to the excess buildup of beta amyloid. Presenilin-1 apparently acts to increase the activity of gamma-secretase, an enzyme that changes a normal protein (amyloid precursor protein or APP) into beta amyloid itself. Furthermore, presenilin-1 might be gamma-secretase. Anti-Beta Amyloid Antibody is useful for researchers interested in TLR signaling and Alzheimer's research.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000
IHC: 1:50-1:200

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For HGF (Source: Uniprot.org, NCBI)

Gene Name

HGF

Full Name

Hepatocyte growth factor

Weight

83.134kDa

Superfamily

peptidase S1 family

Alternative Names

deafness, autosomal recessive 39; DFNB39; EC 3.4.21; EC 3.4.21.7; fibroblast-derived tumor cytotoxic factor; F-TCF; hepatocyte growth factor (hepapoietin A; scatter factor); Hepatopoeitin-A; Hepatopoietin A; HGF; HGFB; HPTA; HPTAhepatocyte growth factor; lung fibroblast-derived mitogen; Scatter factor; SF; SFhepatopoeitin-A HGF DFNB39, F-TCFB, HPTA, SF, HGF hepatocyte growth factor hepatocyte growth factor|fibroblast-derived tumor cytotoxic factor|hepatocyte growth factor (hepapoietin A; scatter factor)|hepatopoietin-A|lung fibroblast-derived mitogen

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on HGF, check out the HGF Infographic

HGF infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for HGF: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

A00089 has been cited in 6 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Hu ZP,Fang XL,Sheng B,Guo Y,Yu YQ.Melatonin inhibits macrophage infiltration and promotes plaque stabilization by upregulating anti-inflammatory HGF/c-Met system in the atherosclerotic rabbit: USPIO-enhanced MRI assessment.Vascul Pharmacol.2020 Apr;127:10
Species: New Zealand Rabbit
A00089 usage in article: APP:WB, SAMPLE:ABDOMINAL AORTA TISSUE, DILUTION:1:250

Corticosterone Mediates the Inhibitory Effect of Restraint Stress on the Migration of Mesenchymal Stem Cell to Carbon Tetrachloride-Induced Fibrotic Liver by Downregulating CXCR4/7 Expression

Pro-osteogenic effects of fibrin glue in treatment of avascular necrosis of the femoral headin vivoby hepatocyte growth factor-transgenic mesenchymal stem cells

HGF-Transgenic MSCs Can Improve the Effects of Tissue Self-Repair in a Rabbit Model of Traumatic Osteonecrosis of the Femoral Head

Wen Q, Zhou L, Zhou C, Zhou M, Luo W, Ma L. J Cell Mol Med. 2012 Jun;16(6):1260-73. Doi: 10.1111/J.1582-4934.2011.01407.X. Change In Hepatocyte Growth Factor Concentration Promote Mesenchymal Stem Cell-Mediated Osteogenic Regeneration.

Zhang Z, Wang G, Ma J, Liu H, Zhang X, Zhu G. Exp Ther Med. 2013 Aug;6(2):427-434. Epub 2013 Jun 6. Effect Of Herba Centellae On The Expression Of Hgf And Mcp-1.

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1 Customer Q&As for Anti-Hepatocyte growth factor HGF Antibody

Question

Is the antigen for A00089 close to N terminal or C terminal?

Verified customer

Asked: 2020-12-30

Answer

For the Anti-Hepatocyte Growth Factor HGF Antibody (A00089), recombinant fusion protein contains a sequence corresponding to amino acids 30-285 of human HGF close to N terminal.

Boster Scientific Support

Answered: 2020-12-31

Order DetailsPrice
A00089-100ul

100ul

$405

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