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Product Info Summary
| SKU: | A05455 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IF, WB |
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Product info
Product Name
Anti-Histamine H2 receptor HRH2 Antibody
View all Histamine H2R Antibodies
SKU/Catalog Number
A05455
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Histamine H2 receptor HRH2 Antibody catalog # A05455. Tested in WB,IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Histamine H2 receptor HRH2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05455)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human GANP.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A05455 is reactive to HRH2 in Human, Mouse, Rat
Applications
A05455 is guaranteed for IF, WB Boster Guarantee
Observed Molecular Weight
111 kDa
Calculated molecular weight
40.098kDa
Background of Histamine H2R
Isoform GANP:Essential for the generation of high-affinity B-cells against T-cell-dependent antigens by affecting somatic hypermutation at the IgV-regions. May have stimulation-dependent DNA primase activity that would generate extra RNA primers in very rapidely proliferating cells and would support clonal expansion of differentiating B-cells By similarity. Involved in the nuclear export of poly(A)-containing mRNAs by acting as a scaffold for the TREX-2 complex. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. Isoform MCM3AP:Acetyltransferase targeting MCM3. Inhibits initiation of DNA replication, but not elongation.
Nobuo Sakaguchi, J. Immunol., Apr 2005; 174: 4485 - 4494.
Kazuhiko Kuwahara, Blood, Apr 2000; 95: 2321 - 2328.
Y Kono, K Maeda, Genes Cells, Aug 2002; 7: 821 - 834.
Kazuhiko Kuwahara, PNAS, Aug 2001; 98: 10279.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
IF: 1:50-1:200
Validation Images & Assay Conditions
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Western blot (WB) analysis of HRH2 polyclonal antibody at 1:500 dilution Lane1:HEK293T cell lysate Lane2:NIH-3T3 cell lysate Lane3:H9C2 cell lysate
Protein Target Info & Infographic
Gene/Protein Information For HRH2 (Source: Uniprot.org, NCBI)
Gene Name
HRH2
Full Name
Histamine H2 receptor
Weight
40.098kDa
Superfamily
G-protein coupled receptor 1 family
Alternative Names
Gastric Receptor 1; Gastric receptor I; H2R; HH2R; Histamine H2 R; histamine H2 receptor; Histamine H2R; histamine receptor H2; HRH2 HRH2 H2R, HH2R histamine receptor H2 histamine H2 receptor|gastric receptor 1|gastric receptor I
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on HRH2, check out the HRH2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for HRH2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Histamine H2 receptor HRH2 Antibody (A05455)
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No publications found for A05455
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Customer Reviews
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