Click image to see more details
Product Info Summary
| SKU: | A10326 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-ILP-2 BIRC8 Antibody
SKU/Catalog Number
A10326
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ILP-2 BIRC8 Antibody (Catalog # A10326). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
ILP-2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-ILP-2 BIRC8 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10326)
Host
Rabbit
Contents
ILP-2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ILP-2 antibody was raised with against a synthetic peptide corresponding to amino acids near the amino terminus of human ILP-2. The immunogen is located within the first 50 amino acids of ILP-2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms of UPK1B are known to exist; this antibody will recognize both isoforms. UPK1B antibody is predicted to not cross-react with other tetraspanin protein family members.
Reactive Species
A10326 is reactive to BIRC8 in Human, Mouse, Rat
Applications
A10326 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
27.089kDa
Background of BIRC8
Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2. ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues. ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
Submit A Review
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ILP-2 antibody can be used for detection of ILP-2 by Western blot at 1 μg/mL. A band at approximately 33 kDa can be detected. Antibody can also be used for immunocytochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of ILP-2 expression in human HepG2 (lane 1) and MOLT4 (lane 2) cell lysates with ILP-2 antibody at 1 μg/mL.
Click image to see more details
Immunocytochemistry of ILP-2 in HepG2 cells with ILP-2 antibody at 10 μg/mL.
Click image to see more details
Immunofluorescence of ILP-2 in HepG2 cells with ILP-2 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For BIRC8 (Source: Uniprot.org, NCBI)
Gene Name
BIRC8
Full Name
Baculoviral IAP repeat-containing protein 8
Weight
27.089kDa
Superfamily
IAP family
Alternative Names
baculoviral IAP repeat containing 8; baculoviral IAP repeat-containing 8; baculoviral IAP repeat-containing protein 8; hILP2; IAP-like protein 2; ILP-2ILP2; Inhibitor of apoptosis-like protein 2; Testis-specific inhibitor of apoptosis BIRC8 ILP-2, ILP2, RNF136, hILP2 baculoviral IAP repeat containing 8 IAP-like protein 2|baculoviral IAP repeat-containing protein 8|inhibitor of apoptosis-like protein 2|testis-specific inhibitor of apoptosis
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on BIRC8, check out the BIRC8 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for BIRC8: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ILP-2 BIRC8 Antibody (A10326)
Hello CJ!
No publications found for A10326
*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-ILP-2 BIRC8 Antibody?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
Be the first to review Anti-ILP-2 BIRC8 Antibody
*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
