Anti-Laminin LAMA1 Monoclonal Antibody

Product Name

Anti-Laminin LAMA1 Monoclonal Antibody

View all LAMA1 Antibodies

SKU/Catalog Number

MA1054
BM1225 is an alternative SKU for this antibody, used in previous lots.

Size

100 μg/vial

Form

Lyophilized

Description

LAMA1 (laminin subunit alpha-1) is an extracellular matrix/basement-membrane component implicated in cell attachment, migration, and tissue organization; frequently used as a structural ECM readout in histology. Assay context: Human/Pig-reactive monoclonal validated for IHC; useful for assessing basement membrane integrity and spatial ECM architecture, and can be contrasted with ECM-degradation signatures such as MMP3 in remodeling phenotypes (putative comparative interpretation).

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Laminin LAMA1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1054)

Host

Mouse

Contents

Mouse IgG in stabilizing components, 1.2% sodium acetate and 0.01mg NaN3.

Clonality

Monoclonal

Clone Number

LAM-89

Isotype

Mouse IgG1

Immunogen

Human laminin.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

MA1054 is reactive to LAMA1 in Human, Pig

Calculated molecular weight

196.5 kDa

Background of LAMA1

Laminin is a heterotrimeric extracellular matrix protein consisting of 3 chains: alpha-1,beta-1 and gamma-1, formerly called beta-2 (LAMA2). This gene is over 260,000 base pairs and contains 64 exons. Laminin is similar with merosin, a basement membrane-associated protein found in placenta, striated muscle, and peripheral nerve, and both of them are members of the same family of basement membrane proteins. And merosin is the same as laminin M, a striated muscle-specific, basal-lamina-associated protein, it may play a primary role in the pathogenesis of that disorder.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

MA1054 is guaranteed for IHC Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Human, feline, pig

Positive Control

IHC: human placenta tissue

Validation Images & Assay Conditions

See full target information LAMA1

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