Anti-POLR3A Antibody

Product Name

Anti-POLR3A Antibody

View all POLR3A Antibodies

SKU/Catalog Number

A06059

Size

100μl

Form

Liquid

Description

Boster Bio Anti-POLR3A Antibody catalog # A06059. Tested in WB applications. This antibody reacts with Human, Monkey, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-POLR3A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06059)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from the N-terminal region of human POLR3A. at AA rangle: 1-80

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A06059 is reactive to POLR3A in Human, Monkey, Mouse

Applications

A06059 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

155.641kDa

Background of POLR3A

Cyclin T2 is a ubiquitously expressed nuclear protein that is a member of the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns that contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. Anti-Cyclin T2 Antibody is useful for researchers interested in HIV research, Gene expression, and cell cycle pathways.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of specific cells using POLR3A Polyclonal antibody.

Gene/Protein Information For POLR3A (Source: Uniprot.org, NCBI)

Alternative Names

DNA-directed RNA polymerase III largest subunit; DNA-directed RNA polymerase III subunit A; DNA-directed RNA polymerase III subunit RPC1; EC 2.7.7.6; hRPC155; POL3A; polymerase (RNA) III (DNA directed) polypeptide A, 155kDa; RNA polymerase III 155 kDa subunit; RNA polymerase III subunit C160; RNA polymerase III subunit RPC155-D; RPC1; RPC155RNA polymerase III subunit C1 POLR3A ADDH, C160, HLD7, RPC1, RPC155, WDRTS, hRPC155 RNA polymerase III subunit A DNA-directed RNA polymerase III subunit RPC1|DNA-directed RNA polymerase III largest subunit|DNA-directed RNA polymerase III subunit A|RNA polymerase III 155 kDa subunit|RNA polymerase III subunit C1|RNA polymerase III subunit C160|RNA polymerase III subunit RPC155-D|polymerase (RNA) III (DNA directed) polypeptide A, 155kDa|polymerase (RNA) III subunit A

For more info on POLR3A, check out the POLR3A Infographic

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In this infographic, you will see the following information for POLR3A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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