Product Info Summary
SKU: | A02099-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC, WB |
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Product info
Product Name
Anti-PTTG1/2/3 (L149) Antibody
SKU/Catalog Number
A02099-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-PTTG1/2/3 (L149) Antibody catalog # A02099-1. Tested in WB,IHC,IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-PTTG1/2/3 (L149) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02099-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Siah-1/2
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02099-1 is reactive to PTTG1 in Human, Mouse, Rat
Applications
A02099-1 is guaranteed for IF, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
22.024kDa
Background of PTTG1
Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) By similarity. Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.
Hateboer G., EMBO J. 14:3159-3169(1995).
Deloukas P., Nature 429:375-381(2004).
Matsuoka S., Science 316:1160-1166(2007).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
IHC: 1:50-1:200
IF: 1:50-1:200
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For PTTG1 (Source: Uniprot.org, NCBI)
Gene Name
PTTG1
Full Name
Securin
Weight
22.024kDa
Superfamily
securin family
Alternative Names
EAP1MGC126883; ESP1-associated protein 1; Esp1-associated protein; hPTTG; pituitary tumor-transforming 1; Pituitary tumor-transforming gene 1 protein; PTTGMGC138276; securin; Tumor-transforming protein 1; TUTR1HPTTG PTTG1 EAP1, HPTTG, PTTG, TUTR1 PTTG1 regulator of sister chromatid separation, securin securin|ESP1-associated protein 1|pituitary tumor-transforming 1|pituitary tumor-transforming gene 1 protein|tumor-transforming protein 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PTTG1, check out the PTTG1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PTTG1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PTTG1/2/3 (L149) Antibody (A02099-1)
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No publications found for A02099-1
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