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Product Info Summary
| SKU: | A01315 |
|---|---|
| Size: | 100μl |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-TCF-1 TCF7 Antibody
SKU/Catalog Number
A01315
Size
100μl
Form
Liquid
Description
Boster Bio Anti-TCF-1 TCF7 Antibody catalog # A01315. Tested in WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-TCF-1 TCF7 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01315)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
8B3A11
Isotype
IgG
Immunogen
Synthesized peptide derived from the N-terminal region of human TCF-1. at AA rangle: 10-90
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01315 is reactive to TCF7 in Human, Mouse
Applications
A01315 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
39 kDa
Calculated molecular weight
41.642kDa
Background of TCF7/TCF1
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC5 belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.
Doppler H, et al. (2005) J Biol Chem. 280(15):15013-15019.
McKinsey TA, et al. (2000) Nature. 408(6808): 106-111.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB, 1:500-1:2000
Validation Images & Assay Conditions
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Western Blot (WB) analysis of specific cells using TCF-1 Polyclonal antibody.
Protein Target Info & Infographic
Gene/Protein Information For TCF7 (Source: Uniprot.org, NCBI)
Gene Name
TCF7
Full Name
Transcription factor 7
Weight
41.642kDa
Superfamily
TCF/LEF family
Alternative Names
FLJ36364; MGC47735; T-cell factor 1; T-cell specific; TCF1; TCF7; TCF-7; transcription factor 7 (T-cell specific, HMG-box) TCF7 TCF-1 transcription factor 7 transcription factor 7|T-cell-factor-7|T-cell-specific transcription factor 1|transcription factor 7 (T-cell specific, HMG-box)
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TCF7, check out the TCF7 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TCF7: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TCF-1 TCF7 Antibody (A01315)
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No publications found for A01315
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