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- Table of Contents
Androgen receptor Antibodies
AND AR ELISA kits, Androgen receptor Proteins
Many biological assays use antibodies to detect Androgen receptor, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Androgen receptor in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Androgen receptor antibodies...
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AR Infographic by Boster Bio
All AR Products
Product
Figures
Specificity
Applications
Price
Human
IP, IF, IHC, ICC, WB
$370
Cat # M00542-1
100 μl
Cat # M00542-1
100 μl
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M00542-2
100 μl
Cat # M00542-2
100 μl
Human
IHC, WB
$370
Cat # M00542-3
100 μl
Cat # M00542-3
100 μl
Human
ELISA
$480
Cat # EKC1029
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1029
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2586
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2586
1 kit, containing two 96-well plates and all necessary reagents
Anti-Androgen Receptor/AR Antibody Picoband®
7 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A00542
100 μg/vial
Cat # A00542
100 μg/vial
Anti-Phospho-JAK2/3 (Tyr966/939) AR Antibody
4 Citations
Human, Mouse, Rat
ELISA, IHC, WB
$380
Cat # A00542Y966
100ul
Cat # A00542Y966
100ul
Human
$628
Cat # LS000367
20 µg, 100 µg
Cat # LS000367
20 µg, 100 µg
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # P00542-2
100 μl/vial
Cat # P00542-2
100 μl/vial
AR Overview
Facts about Androgen receptor.
Androgen receptor (AR)
Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins.
Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.
Gene Information
| Human | |
|---|---|
| Gene Name: | AR |
| Uniprot: | P10275 |
| Entrez: | 367 |
Family
| Belongs to: |
|---|
| nuclear hormone receptor family |
Alternative Names
AIS; Androgen R; androgen receptor; AndrogenR; AR; DHTR; DHTRTFM; Dihydrotestosterone receptorHYSP1; HUMARA; NR3C4; NR3C4KD; Nuclear receptor subfamily 3 group C member 4; SBMA; SMAX1; SMAX1SBMA; spinal and bulbar muscular atrophy
Molecular Weight
Mass (kDA):
99.188 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xq12 |
| Sequence: | X; NC_000023.11 (67544021..67730619) |
Tissue Specificity
Isoform 2 is mainly expressed in heart and skeletal muscle (PubMed:15634333). Isoform 3 is expressed by basal and stromal cells of prostate (at protein level) (PubMed:19244107).
Subcellular Localizations
Nucleus. Cytoplasm. Detected at the promoter of target genes (PubMed:25091737). Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of RACK1.
Diseases
- Malignant Neoplasms
- Malignant Neoplasm Of Prostate
- Prostatic Neoplasms
- Neoplasms
- Carcinoma
- Mammary Neoplasms
- Rhinorrhea
- Malignant Neoplasm Of Breast
- Allergic Rhinitis (disorder)
- Regurgitation
- Inflammation
- Aortic Valve Insufficiency
- Hyperplasia
Pathways
- Cell Proliferation
- Localization
- Acrosome Reaction
- Cell Growth
- Pathogenesis
- Secretion
- Cell Cycle
- Transport
- Fertilization
- Cell Death
- Spermatogenesis
- Methylation
- Aging
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Oxidation
- Acetylation
- Reduction
- Ubiquitination
- Glycosylation
- Sumoylation
- Carboxylation
Research Areas
- Breast Cancer
- Cancer
- Phospho-Specific
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AR
bosterbio.com/bosterbio-gene-info-cards/AR
References
PMID: 3216866 by Lubahn D.B., et al. The human androgen receptor: complementary deoxyribonucleic acid cloning, sequence analysis and gene expression in prostate.
PMID: 3174628 by Chang C., et al. Structural analysis of complementary DNA and amino acid sequences of human and rat androgen receptors.
5 Publications of Boster Androgen receptor Antibodies & ELISA Kits
- PubMed ID: 10.3980/j.issn.2222-3959.2010.01.10, Effects of extract of Buddleja officinalis eye drops on androgen receptors of la...
- PubMed ID: 10.3892/etm.2014.2150, Elevated expression levels of androgen receptors and matrix metalloproteinase-2 ...
- PubMed ID: 27073450, Changes in mitotic reorientation and Wnt/AR signaling in rat prostate epithelial...
- PubMed ID: 26798404, Yangjing Capsule Ameliorates Spermatogenesis in Male Mice Exposed to Cyclophosph...
- PubMed ID: 25667651, Zhang Y, Shen Y, Cao B, Yan A, Ji H. Exp Ther Med. 2015 Mar;9(3):905-908. Epub 2...
*More publications can be found for each product on its corresponding product page