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Bcl-2-interacting killer Antibodies
AND BIK ELISA kits, Bcl-2-interacting killer Proteins
Many biological assays use antibodies to detect Bcl-2-interacting killer, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Bcl-2-interacting killer in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Bcl-2-interacting killer antibodies...
Designing a Western blot for Bcl-2-interacting killer? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the BIK Western Blot GuideDesigning an IHC experiment for Bcl-2-interacting killer? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the BIK IHC GuideBIK Infographic by Boster Bio
All BIK Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK1598
96 wells/kit, with removable strips.
Cat # EK1598
96 wells/kit, with removable strips.
Human HAI-2/SPINT2 ELISA Kit PicoKine®
1 Citations
Human
ELISA
$499
Cat # EK0773
96 wells/kit, with removable strips.
Cat # EK0773
96 wells/kit, with removable strips.
Anti-IKK beta/IKBKB Antibody Picoband®
1 Citations
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9221
100 μg/vial
Cat # PB9221
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IHC, ICC, WB
$370
Cat # PB9755
100 μg/vial
Cat # PB9755
100 μg/vial
Anti-IKK beta IKBKB Rabbit Monoclonal Antibody
2 Citations
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M00118
100 μl
Cat # M00118
100 μl
Anti-IKK beta/IKBKB Antibody Picoband®
2 Citations
Human, Mouse, Rat
WB
$370
Cat # PA2036-1
100 μg/vial
Cat # PA2036-1
100 μg/vial
Human
ELISA, IHC, WB
$370
Cat # A02419-3
100 μg/vial
Cat # A02419-3
100 μg/vial
Mouse, Rat
ELISA, WB
$370
Cat # A02419-4
100 µg/vial
Cat # A02419-4
100 µg/vial
Anti-IKB beta/NFKBIB Antibody Picoband®
1 Citations
Human, Mouse, Rat
IHC, WB
$370
Cat # PB9292
100 μg/vial
Cat # PB9292
100 μg/vial
Human
ELISA
$540
Cat # EKC1971
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC1971
1 kit, containing two 96-well plates and all necessary reagents
Human
ELISA
$480
Cat # EKC1060
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1060
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2074
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2074
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2044
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2044
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2043
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2043
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2042
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2042
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1294
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1294
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1293
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1293
1 kit, containing one 96-well plate and all necessary reagents
Human
ELISA
$540
Cat # EKC2041
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2041
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC1944
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC1944
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse
ELISA
$480
Cat # EKC1312
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1312
1 kit, containing one 96-well plate and all necessary reagents
BIK Overview
Facts about Bcl-2-interacting killer.
Bcl-2-interacting killer (BIK)
Accelerates programmed cell death. Association into the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting action.
Does not interact with BAX. .
Gene Information
| Human | |
|---|---|
| Gene Name: | BIK |
| Uniprot: | Q13323 |
| Entrez: | 638 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Apoptosis inducer NBK; BCL2-interacting killer (apoptosis-inducing); bcl-2-interacting killer; BIK; BIP1; BP4; NBK; NBKapoptosis-inducing NBK
Molecular Weight
Mass (kDA):
18.016 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 22q13.2 |
| Sequence: | 22; NC_000022.11 (43110750..43129712) |
Subcellular Localizations
Endomembrane system; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Around the nuclear envelope, and in cytoplasmic membranes.
Diseases
- Malignant Neoplasms
- Neoplasms
- Lymphoma
- Carcinoma
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Malignant Tumor Of Colon
- Colonic Neoplasms
- Neoplasm Metastasis
- Malignant Paraganglionic Neoplasm
- Multiple Myeloma
- Leukemia
Interacting Proteins
- BCL2
- BCL2A1
- BCL2L1
- BCL2L10
- BCL2L2
- FATE1
Pathways
- Cell Death
- Cell Cycle
- Induction Of Apoptosis
- Localization
- Cell Proliferation
- Programmed Cell Death
- Methylation
- Dna Methylation
- Translation
- Autophagy
- Cell Cycle Arrest
- Cell Growth
- Release Of Cytochrome C From Mitochondria
PTMs
- Cleavage
- Phosphorylation
- Methylation
- Acetylation
- Deacetylation
Research Areas
- Apoptosis
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BIK
bosterbio.com/bosterbio-gene-info-cards/BIK
References
PMID: 7478623 by Boyd J.M., et al. Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins.
PMID: 8816500 by Han J., et al. Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19K.
4 Publications of Boster Bcl-2-interacting killer Antibodies & ELISA Kits
- PubMed ID: 10.3390/antiox10020176, Gastro-Protective Effects of Albizia anthelmintica Leaf Extract on Indomethacin-...
- PubMed ID: 10.3389/fonc.2019.01150, Multi-platform Affinity Proteomics Identify Proteins Linked to Metastasis and Im...
- PubMed ID: 10.1016/j.ejphar.2020.173136, Prolonged overnutrition with fructose or fat induces metabolic derangements in r...
- PubMed ID: 33530540, Nabil M, El Raey MA, Abdo W, Abdelfattah MAO, El-Shazly AM, Sobeh M, Mahmoud MF....
*More publications can be found for each product on its corresponding product page