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- Table of Contents
7 Q&As
Facts about Bcl-2-interacting killer.
Does not interact with BAX. .
Human | |
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Gene Name: | BIK |
Uniprot: | Q13323 |
Entrez: | 638 |
Belongs to: |
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No superfamily |
Apoptosis inducer NBK; BCL2-interacting killer (apoptosis-inducing); bcl-2-interacting killer; BIK; BIP1; BP4; NBK; NBKapoptosis-inducing NBK
Mass (kDA):
18.016 kDA
Human | |
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Location: | 22q13.2 |
Sequence: | 22; NC_000022.11 (43110750..43129712) |
Endomembrane system; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Around the nuclear envelope, and in cytoplasmic membranes.
BIK is a biomarker that has many benefits for researchers. It is highly sensitive. Sensitivity is enhanced to the picogram-level. Secondly, it has been validated for a variety of samples, with a validation procedure and images available upon request. It is also polymer based, which can save you up to 30 minutes when performing IHC. It is supported by the insights of immunogen design and technical support provided by Sanbio, a BeNeLux distributor.
Picokine(r), Quick ELISA is an upgrade of traditional ELISA procedures that can deliver outstanding results in under 90 minutes. They are extremely sensitive and have a simplified protocol. They take less than one hour to complete. PicoKine(r), Quick ELISA kit are validated against a variety bio samples and guaranteed reproducibility. Click here to learn more.
Boster Bio's ELISA kit line contains highly specific antibodies suitable for a variety applications. The antibody range also includes picogram sensitivity ELISA kits, IHC-optimized clonal antibodies and flow cytometry. Boster guarantees that every product will work as described. The antibodies are used in research extensively, with over 12,000 publications. Researchers are protected by Boster Quality Garanty from substandard antibodies.
Picokine (r) Fast ELISA utilizes a solid Phase immunoassay using micro-titration Wells and a biotinylated identification antibody. These antibodies attach to the antigen and create a sandwich structure in one step. The next step is the addition of the Avidin-Biotin-Peroxidase (ABP) substrate. The intensity of the blue product reflects the concentration of the target analyte. PicoKine(r), Quick ELISA has been validated with a variety bio samples.
There are many sizes and configurations of 96-well polystyrene plates that can be used in ELISA. This plate is ideal for this assay. The 96 well polystyrene plate can be washed like the sandwich assay. Boster Bio ELISA products come with pre-determined sample dilution guidelines.
Boster Bio offers a wide selection of options whether you are looking for a custom antibody or an ELISA kit. Boster Bio has extensive sample processing capabilities that allow for custom antibody preparation and testing. They also offer custom BeNeLux deliveries. Get in touch with us today to find out more about custom Boster Bio services. To discuss your custom sample requests, you can also reach out to us. Below are the services offered by us.
Immunohistochemistry is an advanced technique of staining cell tissues to detect antigens and haptens. Boster Bio can adjust antibodies, dilutions ratios, and cell- and tissue dilutions according to your specific requirements. You can also order Multiplex Immunohistochemistry, a high-throughput service that allows detection of multiple targets. Boster Bio is an excellent choice when it comes to custom IHC.
Many applications can be customized with Western Blots. Boster offers custom services to extract the total protein from tissues, create premade Western Blots, immunostain them with any antibody, and analyze quantitatively the results. Boster Bio is a leading ELISA manufacturer worldwide and also offers custom CRO support for diagnostic assay creation. Customers can rely on their experience and technical expertise to meet their needs.
The company is known to produce high-quality, IHC optimised polyclonals as well as picogram sensitivity ELISA Kits. The company's antibody catalog contains over 12,000 products. It has been validated against over 250 different tissue types and untransfected cells to be valid for IHC, WB, and Flow applications. Boster also offers a quality guarantee that ensures each product works as it is advertised.
This antibody is designed for the detection of p21 protein in human colon tissue. Boster Bio IHC-optimized Polyclonal Antibodies detect this protein in FFPE Sections. The antibodies are optimized for IHC, minimizing cross-reactivity to other antigens. The Boster Bio polyclonal antibodies can be used for different purposes. You can use the antibodies for a variety purposes, including to detect DNA and protein-containing cell targets.
Boster Bio offers ELISA kit and isotype control kits in addition to primary antibodies. Boster Bio's custom antibodies are made in-house, which helps to ensure that they meet high quality standards. ELISA kits as well as secondary antibodies are optimized for maximum sensitivity to ensure high-quality results. Boster's products can be purchased at competitive prices, including a package of $600 for rare species or discontinued antibodies.
IHC is a staining method that can be used to analyze cells tissues. It is used to detect antigens in these cells. Boster Bio IHC-optimized Polyclonal Antibodies can be used with less reagents. Boster Bio has over 16,000 approved antibodies and is ready to serve your needs with its high-throughput screening technique.
PMID: 7478623 by Boyd J.M., et al. Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins.
PMID: 8816500 by Han J., et al. Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19K.