- Table of Content
Also binds to the PLK and PIM1 promoters. Plays an important role in oocyte and preimplantation embryo development by activating or repressing transcription.
|CTCF zinc-finger protein family|
|Sequence:||16; NC_000016.10 (67562526..67639185)|
Ubiquitous. Absent in primary spermatocytes.
Nucleus, nucleoplasm. Chromosome. Chromosome, centromere. May translocate to the nucleolus upon cell differentiation. Associates with both centromeres and chromosomal arms during metaphase. Associates with the H19 ICR in mitotic chromosomes. May be preferentially excluded from heterochromatin during interphase.