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- Table of Contents
EBI3 Antibodies
AND EBI3 ELISA kits, EBI3 Proteins
Many biological assays use antibodies to detect EBI3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EBI3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EBI3 antibodies...
Designing a Western blot for EBI3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the EBI3 Western Blot GuideDesigning an IHC experiment for EBI3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the EBI3 IHC GuideEBI3 Infographic by Boster Bio
All EBI3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00300-1
100 μg/vial
Cat # M00300-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00327-2
100 μg/vial
Cat # M00327-2
100 μg/vial
Human, Mouse, Rat
ELISA, IF, IHC-P, WB
$481
Cat # A07190-1
0.1 mg
Cat # A07190-1
0.1 mg
Human
Cell Culture
$77
Cat # PROTQ14213-3
5ug,20ug,100ug
Cat # PROTQ14213-3
5ug,20ug,100ug
Mouse
Cell Culture
$77
Cat # PROTO35228-1
5ug,20ug,100ug
Cat # PROTO35228-1
5ug,20ug,100ug
EBI3 Overview
Facts about Interleukin-27 subunit beta.
Interleukin-27 subunit beta (EBI3)
Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 contains pro- and anti-inflammatory properties, that can modulate T- helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has varied effects on innate immune cells.
Among its target cells are CD4 T-helper cells that can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells.
Gene Information
| Human | |
|---|---|
| Gene Name: | EBI3 |
| Uniprot: | Q14213 |
| Entrez: | 10148 |
Family
| Belongs to: |
|---|
| type I cytokine receptor family |
Alternative Names
cytokine receptor; EBI3; EBI-3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; Epstein-Barr virus-induced gene 3 protein; IL-27 beta; IL-27 subunit beta; IL27B; IL-27B; IL35 EBI3; IL-35 EBI3; interleukin-27 subunit beta
Molecular Weight
Mass (kDA):
25.396 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.3 |
| Sequence: | 19; NC_000019.10 (4229196..4237539) |
Subcellular Localizations
Secreted.
Diseases
- Inflammation
- Autoimmune Reaction
- Colitis
- Neoplasms
- Inflammatory Bowel Diseases
- Intestinal Diseases
- Autoimmune Diseases
- Asthma
- Encephalomyelitis
- Lymphoma
- Crohn Disease
- Ulcer
- Experimental Autoimmune Encephalomyelitis
Interacting Proteins
- IL27
Pathways
- Immune Response
- Secretion
- Cytokine Production
- Cell Proliferation
- T Cell Proliferation
- Cell Differentiation
- Pathogenesis
- Cell Activation
- T Cell Activation
- Interferon-gamma Production
- Inflammatory Response
- Cell Development
- Complement Activation
PTMs
- Phosphorylation
- Cleavage
Research Areas
- Apoptosis
- Cancer
- Cytokine Research
- Hypoxia
- Immunology
- Innate Immunity
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EBI3
bosterbio.com/bosterbio-gene-info-cards/EBI3
References
PMID: 8551575 by Devergne O., et al. A novel interleukin-12 p40-related protein induced by latent Epstein- Barr virus infection in B lymphocytes.
PMID: 9342359 by Devergne O., et al. Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin.
11 Publications of Boster EBI3 Antibodies & ELISA Kits
- PubMed ID: PMID:27293989, Recombinant Newcastle disease virus (rL-RVG) triggers autophagy and apoptosis in...
- PubMed ID: 10.3892/ijo.2015.3039, Autophagy is involved in recombinant Newcastle disease virus (rL-RVG)-induced ce...
- PubMed ID: 10.1093/jnen/nlaa007, Generation and Characterization of Novel Monoclonal Antibodies Targeting p62/se...
- PubMed ID: -, Zhiwei Liao,Suyun Li,Rong Liu,Xiaobo Feng,Yunsong Shi,Kun Wang,Shuai Li,Yukun Zh...
- PubMed ID: -, Zhang Tao,Xiaoqing Zhou,Yan Zhang,Wenfeng Pu,Yi Yang,Fuxia Wei,Qian Zhou,Lin Zha...
- PubMed ID: -, Liu, J.,Qin, X.,Ma, W.,Jia, S.,Zhang, X.,Yang, X. ... Jin, F. (2021). Corilagin ...
- PubMed ID: 32098126, Zhong W,Tang X,Liu Y,Zhou C,Liu P,Li E,Zhong P,Lv H,Zou Q,Wang M.Benzoxazole Der...
- PubMed ID: 32425551, Liu X,Feng C,Wei G,Kong W,Meng H,Du Y,Li J.Mitofusin1 Is a Major Mediator in Glu...
- PubMed ID: 32015954, Yuan H,Wang Y,Chen H,Cai X.Protective effect of flavonoids from Rosa roxburghii ...
- PubMed ID: 31900522, Song L,Yao L,Zhang L,Piao Z,Lu Y.Schizandrol A protects against Aβ1-42-induced ...
- PubMed ID: 29085598, Regulation of autophagy by AMP-activated protein kinase/sirtuin 1 pathway reduce...
*More publications can be found for each product on its corresponding product page