FCGR2B Antibodies

AND FCGR2B ELISA kits, FCGR2B Proteins

Many biological assays use antibodies to detect FCGR2B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FCGR2B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FCGR2B antibodies...

We validate the specificity of these antibodies to FCGR2B by testing them on tissues known to express FCGR2B positively and negatively. Browse below to find the FCGR2B antibody that suites your experiment. We have 12 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for FCGR2B? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the FCGR2B Western Blot Guide

Designing an IHC experiment for FCGR2B? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the FCGR2B IHC Guide

FCGR2B Infographic by Boster Bio

All FCGR2B Products

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Product

Figures

Specificity

Applications

Price

Human CD32 PicoKine® Quick ELISA Kit

Human

ELISA

$499
Cat # FEK1312
96 wells/kit, with removable strips.

Mouse Fc Gamma RII/RIII (CD32/CD16)(Fcgr2b/Fcgr3) PicoKine® Quick ELISA Kit

Mouse

ELISA

$499
Cat # FEK1313
96 wells/kit, with removable strips.

Human CD32/FCGR2b/c ELISA Kit EZ-Set™ (DIY Antibody Pairs)

Human

ELISA

$500
Cat # EZ1312
For 5 plates, 96 wells each

Human Fc gamma RIIB/C (CD32b/c)(FCGR2B/C) ELISA Kit PicoKine®

Human

ELISA

$750
Cat # EK1312
96 wells/kit, with removable strips.

Mouse Fc gamma RII/RIII (CD32/CD16)(Fcgr2b/Fcgr3) ELISA Kit PicoKine®

Mouse

ELISA

$750
Cat # EK1313
96 wells/kit, with removable strips.

CD32B (FCGR2B) (NM_004001) Human Over-expression Lysate

CD32B (FCGR2B) Human Over-expression Lysates NM_001002273

Human

$628
Cat # LS002213
20 µg, 100 µg

SHIP1 (Phospho-Tyr1021) Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from HepG2 cells treated with TNF 200NG/ML 30

Human, Mouse, Rat

ELISA

$540
Cat # EKC2179
1 kit, containing two 96-well plates and all necessary reagents

Anti-CD32 FCGR2B Antibody

1 Citations

Western Blot analysis of SH-SY5Y cells using CD32 Polyclonal Antibody diluted at 1:1000

Western blot analysis of lysates from 293, HepG2, and HeLa cells, treated with PMA 125ng/ml 30

Immunohistochemical analysis of paraffin-embedded human tonsil

Human, Mouse, Rat

ELISA, IF, IHC, WB

$380
Cat # A01690-1
100ul

CD32B (FCGR2B) (NM_001002275) Human Recombinant Protein

Coomassie blue staining of purified FCGR2B protein

$1062
Cat # PROTP31994
20 µg

CD32 (Phospho-Tyr292) Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from K562 cells treated with PMA 125ng/ml 30

Human, Mouse, Rat

ELISA

$540
Cat # EKC2147
1 kit, containing two 96-well plates and all necessary reagents

CD32 Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from 293/HepG2/HeLa cells

Human, Mouse, Rat

ELISA

$480
Cat # EKC1100
1 kit, containing one 96-well plate and all necessary reagents

Anti-CD32-B FCGR2B Antibody

Human

$405
Cat # A01690
100ul

FCGR2B Overview

Facts about Low affinity immunoglobulin gamma Fc region receptor II-b.

FCGR2B 3D structure. Source: alphafold

Low affinity immunoglobulin gamma Fc region receptor II-b (FCGR2B)

Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor.

Involved in many different effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B- cells. Binding to this receptor results in down-modulation of earlier state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or through another Fc receptor.

Gene Information

Human
Gene Name:	FCGR2B
Uniprot:	P31994
Entrez:	2213

Family

Belongs to:

No superfamily

Alternative Names

CD32 antigen; CD32b; CD32Fc fragment of IgG, low affinity II, receptor for (CD32); CDw32; Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc gamma RIIB; FCG2; Fc-gamma RII-b; fc-gamma-RIIb; FCGR2; FCGR2B; FcgRIIB; FCRIIB; fcRII-b; IGFR2; IgG Fc receptor II-b; low affinity immunoglobulin gamma Fc region receptor II-b

Molecular Weight

Mass (kDA):
34.044 kDA

Genomic Context


Human

Location:	1q23.3
Sequence:	1; NC_000001.11 (161647243..161678654)

Tissue Specificity

Is the most broadly distributed Fc-gamma- receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.

Diseases

Autoimmune Reaction
Lupus Erythematosus, Systemic
Autoimmune Diseases
Autoimmunity
Inflammation
Arthritis
Rheumatoid Arthritis
Purpura, Thrombocytopenic, Idiopathic
Glomerulonephritis
Lymphoma
Neoplasms
Dysequilibrium Syndrome
Nephritis

Anaphylaxis
Periodontitis
B-cell Lymphomas
Purpura
Thrombocytopenic Purpura
Decreased Immunologic Activity [pe]
Asthma

Interacting Proteins

IGHG1
INPP5D
NCK1
PLCG1
PTPN6

Pathways

Pathogenesis
Cell Activation
Immune Response
B Cell Activation
Phagocytosis
Anaphylaxis
Secretion
Cell Differentiation
Adaptive Immune Response
Cell Proliferation
B Cell Differentiation
Inflammatory Response
Sensitization

Endocytosis
Cell Death
T Cell Activation
Humoral Immune Response
Neutrophil Activation
Cell Development
Cytokine Production

PTMs

Phosphorylation
Dephosphorylation
Biotinylation

Citrullination
Acetylation
Methylation

Research Areas

Immunology

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FCGR2B

References

PMID: 2531080 by Stuart S.G., et al. Human IgG Fc receptor (hFcRII; CD32) exists as multiple isoforms in macrophages, lymphocytes and IgG-transporting placental epithelium.

PMID: 2529342 by Brooks D.G., et al. Structure and expression of human IgG FcRII(CD32). Functional heterogeneity is encoded by the alternatively spliced products of multiple genes.