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- Table of Contents
GFRA1 Antibodies
AND GFRA1 ELISA kits, GFRA1 Proteins
Many biological assays use antibodies to detect GFRA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GFRA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GFRA1 antibodies...
Designing a Western blot for GFRA1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the GFRA1 Western Blot GuideGFRA1 Infographic by Boster Bio
All GFRA1 Products
Product
Figures
Specificity
Applications
Price
Human
IHC, WB
$370
Cat # PB9202
100 μg/vial
Cat # PB9202
100 μg/vial
Human
$960
Cat # LS002674
20 µg, 100 µg
Cat # LS002674
20 µg, 100 µg
GFRA1 Overview
Facts about GDNF family receptor alpha-1.
GDNF family receptor alpha-1 (GFRA1)
Receptor for GDNF.
Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity).. .
Gene Information
| Human | |
|---|---|
| Gene Name: | GFRA1 |
| Uniprot: | P56159 |
| Entrez: | 2674 |
Family
| Belongs to: |
|---|
| GDNFR family |
Alternative Names
DKFZp313E1012; DKFZp686J0156; GDNF family receptor alpha 1; GDNF family receptor alpha-1; GDNF R alpha-1; GDNF receptor alpha-1; GDNFRAGFR-ALPHA-1; GDNFR-alpha-1; GDNFRMGC23045; GFR alpha1; GFR alpha-1; GFRA1; GFRa-1; GFR-alpha-1; Glial cell line-derived neurotrophic factor receptor alpha; GPI-linked anchor protein; PI-linked cell-surface accessory protein; RET ligand 1; RET1L; RETL1FLJ10561; TGF-beta related neurotrophic factor receptor 1; TGF-beta-related neurotrophic factor receptor 1; TRNR1FLJ31546
Molecular Weight
Mass (kDA):
51.456 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 10q25.3 |
| Sequence: | 10; NC_000010.11 (116056925..116273645, complement) |
Subcellular Localizations
Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus, trans-Golgi network. Endosome. Endosome, multivesicular body. Localizes mainly to the plasma membrane. In the presence of SORL1, shifts to vesicular structures, including trans-Golgi network, endosomes and multivesicular bodies.
Diseases
- Nervousness
- Neoplasms
- Hirschsprung Disease
- Malignant Neoplasms
- Carcinoma
- Endocrine Gland Neoplasms
- Malignant Neoplasm Of Thyroid
- Multiple Endocrine Neoplasia
- Tissue Adhesions
- Multiple Endocrine Neoplasia Type 2a
- Medullary Carcinoma Of Thyroid
- Parkinson Disease
- Congenital Abnormality
Pathways
- Spermatogenesis
- Cell Proliferation
- Pathogenesis
- Localization
- Cell Death
- Cell Adhesion
- Innervation
- Regeneration
- Kidney Development
- Cell Migration
- System Development
- Secretion
- Neuroprotection
PTMs
- Phosphorylation
- Reduction
- Biotinylation
- Phosphorothioation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GFRA1
bosterbio.com/bosterbio-gene-info-cards/GFRA1
References
PMID: 8674117 by Jing S., et al. GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF.
PMID: 9177201 by Sanicola M., et al. Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins.
1 Publications of Boster GFRA1 Antibodies & ELISA Kits
- PubMed ID: 33989617, Zhu WQ,Cai NN,Jiang Y,Yang R,Shi JZ,Zhu CL,Zhang BY,Tang B,Zhang XM.Survivable p...
*More publications can be found for each product on its corresponding product page