Many biological assays use antibodies to detect Histone H1.1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone H1.1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone H1.1 antibodies...
We validate the specificity of these antibodies to Histone H1.1 by testing them on tissues known to express H1-1 positively and negatively. Browse below to find the H1-1 antibody that suites your experiment. We have 46 of these antibodies and many publications and validation images.
If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers.
Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity). .
Gene Information
Human
Gene Name:
H1-1
Uniprot:
Q02539
Entrez:
3024
Family
Belongs to:
histone H1/H5 family
Alternative Names
Histone H1.1
Molecular Weight
Mass (kDA): 21.842 kDA
Genomic Context
Human
Location:
6p22.2
Sequence:
6; NC_000006.12 (26017032..26017787, complement)
Subcellular Localizations
Nucleus. Chromosome. Mainly localizes in euchromatin.
Interacting Proteins
HIST2H2AB
TPPP
PTMs
Acetylation
Citrullination
Hydroxylation
Phosphoprotein
For details, visit: bosterbio.com/bosterbio-gene-info-cards/H1-1
References
PMID: 2759094 by Eick S., et al. Human H1 histones: conserved and varied sequence elements in two H1 subtype genes.
PMID: 8003976 by Parseghian M.H., et al. A proposal for a coherent mammalian histone H1 nomenclature correlated with amino acid sequences.
13 Publications of Boster Histone H1.1 Antibodies & ELISA Kits