Many biological assays use antibodies to detect MAL, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MAL in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MAL antibodies...
We validate the specificity of these antibodies to MAL by testing them on tissues known to express MAL positively and negatively. Browse below to find the MAL antibody that suites your experiment. We have 95 of these antibodies and many publications and validation images.
If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.
Designing a Western blot for MAL?
The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Could be an important element in vesicular trafficking cycling between the Golgi complex and the apical plasma membrane. Could be involved in myelin biogenesis and/or myelin function.
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Gene Information
Human
Gene Name:
MAL
Uniprot:
P21145
Entrez:
4118
Family
Belongs to:
MAL family
Alternative Names
mal, T-cell differentiation protein; myelin and lymphocyte protein; T-cell differentiation protein MAL; T-lymphocyte maturation-associated protein
Molecular Weight
Mass (kDA): 16.714 kDA
Genomic Context
Human
Location:
2q11.1
Sequence:
2; NC_000002.12 (95025655..95053992)
Subcellular Localizations
Membrane; Multi-pass membrane protein.
Diseases
Malignant Neoplasms
Neoplasms
Carcinoma
Meleda Disease
Pain
Allergy
Cerebrovascular Accident
Keratosis
Palmoplantar Keratosis
Absence Epilepsy
Skin Neoplasms
Actinic Keratosis
Food Allergy
Epilepsy
Basal Cell Carcinoma
Inflammation
Dermatologic Disorders
Malignant Squamous Cell Neoplasm
Erythema
Interacting Proteins
BTK
EDA
FIBCD1
KLRC1
LDLRAD1
LSMEM1
SMIM3
USP7
Pathways
Transport
Localization
Immune Response
Pathogenesis
Fermentation
Methylation
Cytokine Production
Innate Immune Response
Glycosylation
Maltose Transport
Secretion
Excretion
Inflammatory Response
Sensitization
Cell Death
Cell Migration
Rna Interference
Hypersensitivity
Myelination
Cell Proliferation
PTMs
Phosphorylation
Methylation
Glycosylation
Cleavage
Oxidation
Reduction
Ubiquitination
Biotinylation
Demethylation
Deacetylation
Acetylation
Carboxylation
Deamination
Ribosylation
Hydroxylation
Dephosphorylation
Acylation
Nitration
Amination
Deglycosylation
Research Areas
Apoptosis
For details, visit: bosterbio.com/bosterbio-gene-info-cards/MAL
References
PMID: 3494249 by Alonso M.A., et al. cDNA cloning and sequence of MAL, a hydrophobic protein associated with human T-cell differentiation.
PMID: 8088843 by Rancano C., et al. Alternative splicing of human T-cell-specific MAL mRNA and its correlation with the exon/intron organization of the gene.
3 Publications of Boster MAL Antibodies & ELISA Kits
PubMed ID: 10.3892/mmr.2019.10888, Comparative proteomic and genomic analyses of Brucella abortus biofilm and plank...