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- Table of Contents
2 Citations 9 Q&As
1 Citations 1 Q&As
2 Citations 9 Q&As
1 Citations
1 Citations
Facts about Oncostatin-M.
Stimulates proliferation of AIDS-KS cells. It modulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells.
Human | |
---|---|
Gene Name: | OSM |
Uniprot: | P13725 |
Entrez: | 5008 |
Belongs to: |
---|
LIF/OSM family |
MGC20461; oncostatin M; oncostatin-M; OSM
Mass (kDA):
28.484 kDA
Human | |
---|---|
Location: | 22q12.2 |
Sequence: | 22; NC_000022.11 (30262829..30266851, complement) |
Secreted.
The Boster Bio: OSM Marker monoclonal antibody offers multiple benefits. Here, we'll review the benefits, ordering process, and benefits of using the monoclonal antibody. Also, we'll talk about how to purchase a sample to see if it works for your research. Let's get started! Purchasing a sample is easy! To get a sample, you can go to bosterbio.com and fill out a form.
The benefits of using anti-CD68 (Macrophage-Marker) monoclonal antibody are countless. In addition to enabling researchers to target immune cells in their studies, the molecule is also useful for the diagnosis of diseases. It binds to a lectin present on organs and tissues that enables macrophages to homing. Macrophages that express CD68 can also crawl over other cells and tissues.
Boster's anti-CD68 (Macrophage Marker) monoclonal antibody is suitable for immunofluorescence staining of kidney paraffin sections. The sections were first treated with the monoclonal anti-CD68 antibody for 1 hour at room temperature. Then, a secondary Cy3-conjugated goat anti-mouse antibody (PAB101), followed by a corresponding a-SMA antibody. Finally, the sections were fixed and imaged using an Axio Imager Z2m confocal system and Zeiss LSM800 inverted stand.
Boster's anti-CD68 (Macrophage Marker) monoclonal antibody has been shown to inhibit NF-kB signaling, a pathway regulated by the p38MAPK/ERK amplification loop. By inhibiting this pathway, MAP4K4-deficient cells show a lower inflammatory response and reduced adhesion to endothelium. It also inhibits NF-kB signaling, which is necessary for the immune system.
The anti-CD68 monoclonal antibody is a highly specific reagent for detecting macrophages in cancer samples. It also identifies the presence of TAMs, M2 macrophages, and CD163-positive cells. In addition, it has been shown that Boster's anti-CD68 (Macrophage Marker) monoclonal antibody also binds to S100A4, a small Ca2+ binding protein.
Unlike other antibodies, this anti-CD68 monoclonal antibody also supports research. It can be used as a reference for standard and specialized applications. Researchers can submit results for research in special samples or species and get credits for their work. These benefits are applicable to all scientists worldwide. The use of this anti-CD68 monoclonal antibody should be considered carefully before using it.
UUO mimics the pathophysiology of chronic obstructive nephropathy. UUO induces renal fibrosis by triggering myofibroblast activation and deposition of extracellular matrix (ECM). Sorafenib treatment inhibits the production of these pro-inflammatory cytokines.
In one study, researchers found that overexpression of MYDGF in bone marrow improved endothelial function and reduced leukocyte apoptosis. Additionally, the anti-MYDGF treatment reduced IL-1b and IL-6 levels in the MAECs, reducing inflammation and IR. Despite the positive results, the trial is not yet fully conclusive, but the data are promising.
How can I order a sample of the OSM marker? Boster Bio is a biotechnology company focused on the development of anticancer cytokines. They provide a variety of products, including the OSM marker. This cytokine is produced by human cells and is part of the interleukin-6 family. Oncostatin M has a gene mapped to 22q12.2 and is most closely related to leukemia inhibitory factor. This anti-tumor cytokine inhibits proliferation and changes in cellular morphology in tumor cell lines. Its receptors are comprised of Gp130, OSMR, and LIFR.
OSM stands for OpenStreetMap, which is a map database built by crowd-sourced geographic data. The OpenStreetMap Foundation provides the map data for free visualization, querying, and download under an open license. This means that anyone can view and modify the data. Purchasing a sample of the OSM marker will allow you to get a sample of the quality of the map data before making a purchase.
Buying a sample of the OSM marker is not a bad idea. Once you have the data, you can use it in your application. OSM also allows users to add all kinds of features that are not included on the base map. For example, you can use larger overlay images to display features that aren't included on the base map. You can trace a line over the base map to create the overlay, and then invoke it just like you would any other type of marker image file. User:J. Johnson has written a detailed guide on how to create an overlay.
PMID: 2779549 by Malik N., et al. Molecular cloning, sequence analysis, and functional expression of a novel growth regulator, oncostatin M.
PMID: 3540948 by Zarling J.M., et al. Oncostatin M: a growth regulator produced by differentiated histiocytic lymphoma cells.
*More publications can be found for each product on its corresponding product page