- Table of Contents
Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May stop the recycling of LDLR from endosomes to the cell surface or guide it to lysosomes for degradation.
|peptidase S8 family|
Hepatocytes, kidney mesenchymal cells, intestinal ileum, colon epithelia and embryonic brain telencephalon neurons.
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